Pennington Biomedical Research Center, Baton Rouge, LA 70808-4124, USA.
Obes Facts. 2013;6(4):317-24. doi: 10.1159/000354712. Epub 2013 Aug 9.
Waist circumference (WC) is a useful anthropometric tool to estimate cardiometabolic risk. However, BMI influences the relationship between WC and health. This study determined BMI-, sex- and race-specific WC thresholds.
The study sample included 6,452 whites and African Americans (AA) aged 18-64 years. WC, BMI, and cardiovascular risk factors were assessed in the clinic. An elevated cardiometabolic risk was defined as the presence of ≥2 cardiometabolic risk factors. Receiver Operating Characteristic (ROC) curves were used to determine BMI-, sex-, and race-specific WC thresholds.
Based on logistic regression, elevated WC within each BMI category was associated with higher cardiometabolic risk. The respective optimal BMI-specific WC thresholds for white women, AA women, white men, and AA men were as follows: 72, 76, 82, and 78 cm for normal-weight (18.5-24.9 kg/m(2)); 87, 85, 95, and 92 cm for overweight (25-29.9 kg/m(2)); 97, 97, 107, and 104 cm for obese I (30-34.9 kg/m(2)); and 111, 110, 120, and 119 cm for obese II+ (≥35 kg/m(2)) participants. Sensitivities ranged from 52.7 to 73.3%, and specificities ranged from 57.1 to 73.5%.
The proposed optimal BMI-, sex-, and race-specific WC thresholds are warranted for use in the clinical setting until representative standards become available based on results from longitudinal studies.
腰围（WC）是一种评估心血管代谢风险的有用人体测量工具。然而，BMI 会影响 WC 与健康之间的关系。本研究确定了 BMI、性别和种族特异性的 WC 切点。
研究样本包括 6452 名年龄在 18-64 岁的白人和非裔美国人（AA）。在诊所评估 WC、BMI 和心血管危险因素。心血管代谢风险升高定义为存在≥2 个心血管代谢风险因素。采用受试者工作特征（ROC）曲线确定 BMI、性别和种族特异性的 WC 切点。
基于逻辑回归，在每个 BMI 类别内，升高的 WC 与更高的心血管代谢风险相关。白人女性、AA 女性、白人男性和 AA 男性分别对应的最佳 BMI 特异性 WC 切点如下：正常体重（18.5-24.9 kg/m2）：女性 72cm、女性 76cm、男性 82cm、男性 78cm；超重（25-29.9 kg/m2）：女性 87cm、女性 85cm、男性 95cm、男性 92cm；肥胖 I （30-34.9 kg/m2）：女性 97cm、女性 97cm、男性 107cm、男性 104cm；肥胖 II+（≥35 kg/m2）：女性 111cm、女性 110cm、男性 120cm、男性 119cm。敏感度范围为 52.7%-73.3%，特异度范围为 57.1%-73.5%。
在基于纵向研究结果制定出有代表性的标准之前，建议在临床环境中使用这些最佳的 BMI、性别和种族特异性的 WC 切点。
