Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Obesity (Silver Spring). 2011 Mar;19(3):671-4. doi: 10.1038/oby.2010.201. Epub 2010 Sep 16.
Although waist circumference (WC) is a marker of visceral adipose tissue (VAT), WC cut-points are based on BMI category. We compared WC-BMI and WC-VAT relationships in blacks and whites. Combining data from five studies, BMI and WC were measured in 1,409 premenopausal women (148 white South Africans, 607 African-Americans, 186 black South Africans, 445 West Africans, 23 black Africans living in United States). In three of five studies, participants had VAT measured by computerized tomography (n = 456). Compared to whites, blacks had higher BMI (29.6 ± 7.6 (mean ± s.d.) vs. 27.6 ± 6.6 kg/m², P = 0.001), similar WC (92 ± 16 vs. 90 ± 15 cm, P = 0.27) and lower VAT (64 ± 42 vs. 101 ± 59 cm², P < 0.001). The WC-BMI relationship did not differ by race (blacks: β (s.e.) WC = 0.42 (.01), whites: β (s.e.) WC = 0.40 (0.01), P = 0.73). The WC-VAT relationship was different in blacks and whites (blacks: β (s.e.) WC = 1.38 (0.11), whites: β (s.e.) WC = 3.18 (0.21), P < 0.001). Whites had a greater increase in VAT per unit increase in WC. WC-BMI and WC-VAT relationships did not differ among black populations. As WC-BMI relationship did not differ by race, the same BMI-based WC guidelines may be appropriate for black and white women. However, if WC is defined by VAT, race-specific WC thresholds are required.
尽管腰围 (WC) 是内脏脂肪组织 (VAT) 的标志物，但 WC 切点是基于 BMI 类别。我们比较了黑人和白人中 WC-BMI 和 WC-VAT 的关系。将来自五项研究的数据合并，在 1409 名绝经前妇女（148 名南非白人、607 名非裔美国人、186 名南非黑人、445 名西非人、23 名生活在美国的非洲黑人）中测量了 BMI 和 WC。在五项研究中的三项研究中，通过计算机断层扫描 (CT) 测量了参与者的 VAT（n = 456）。与白人相比，黑人的 BMI 更高（29.6 ± 7.6（均值 ± s.d.） vs. 27.6 ± 6.6 kg/m²，P = 0.001），WC 相似（92 ± 16 vs. 90 ± 15 cm，P = 0.27），VAT 较低（64 ± 42 vs. 101 ± 59 cm²，P < 0.001）。种族对 WC-BMI 关系没有影响（黑人：β（s.e.）WC = 0.42（0.01），白人：β（s.e.）WC = 0.40（0.01），P = 0.73）。WC-VAT 关系在黑人和白人中不同（黑人：β（s.e.）WC = 1.38（0.11），白人：β（s.e.）WC = 3.18（0.21），P < 0.001）。白人每增加单位 WC，VAT 增加更多。WC-BMI 和 WC-VAT 关系在黑人人群中没有差异。由于 WC-BMI 关系不因种族而异，因此基于 BMI 的相同 WC 指南可能适用于黑人和白人女性。然而，如果 WC 由 VAT 定义，则需要特定种族的 WC 阈值。
