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睡眠时间和午睡与肥胖风险的关系:SUN 地中海队列研究。

Association between sleeping hours and siesta and the risk of obesity: the SUN Mediterranean Cohort.

机构信息

Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain.

出版信息

Obes Facts. 2013;6(4):337-47. doi: 10.1159/000354746. Epub 2013 Aug 10.

Abstract

OBJECTIVES

Our aim was to investigate the association between sleeping hours at night and during the siesta and the incidence of obesity in a Mediterranean cohort.

METHODS

After a median of 6.5 years of follow-up, we included 10,532 or 9,470 participants without chronic disease or obesity at baseline for analyzing the association between the incidence of obesity and nocturnal sleep duration or having siesta. Sleeping hours and siesta were assessed at baseline. Weight was recorded at baseline and every 2 years during the follow-up. The outcome was the incidence of obesity during follow-up among participants with initial BMI <30 kg/m(2).

RESULTS

During follow-up we observed 446 new cases of obesity in the analysis of nocturnal sleep duration. Sleeping less than 5 h at night was associated with a higher risk of becoming obese compared to sleeping between 7 and <8 h (HR 1.94; 95% CI 1.19-3.18; p for quadratic trend = 0.06) after adjusting for potential confounders. During follow-up, we observed 396 incident cases of obesity in the analysis of siesta. Those who took a siesta for 30 min/day had a 33% lower risk of becoming obese (HR 0.67; 95% CI 0.46-0.96; p for quadratic trend = 0.13) compared to those who did not take siesta.

CONCLUSION

Our results suggest that short nocturnal sleep duration could be a modifiable risk factor for obesity. It is possible that this association may be stronger among men and subjects who experienced previous weight gain. Additionally, siesta might be a novel and independent protective factor for obesity; however, confirmatory studies are needed.

摘要

目的

我们旨在研究夜间和午睡时的睡眠时间与肥胖发生率之间的关系,以评估地中海人群的肥胖发生率。

方法

在中位数为 6.5 年的随访期间,我们纳入了 10532 或 9470 名基线时无慢性疾病或肥胖的参与者,以分析肥胖发生率与夜间睡眠时间或午睡之间的关系。在基线时评估睡眠时间和午睡情况。在基线和随访期间的每两年记录一次体重。结局为基线 BMI<30kg/m2的参与者随访期间的肥胖发生率。

结果

在随访期间,我们观察到 446 例新的肥胖病例。与睡眠时间为 7-<8 小时相比,夜间睡眠时间<5 小时与肥胖风险升高相关(HR 1.94;95%CI 1.19-3.18;p 趋势=0.06),校正了潜在混杂因素后。在随访期间,我们观察到 396 例新的肥胖病例。与不午睡相比,每天午睡 30 分钟的参与者肥胖风险降低了 33%(HR 0.67;95%CI 0.46-0.96;p 趋势=0.13)。

结论

我们的结果表明,夜间睡眠时间短可能是肥胖的可改变风险因素。这种关联在男性和有体重增加史的人群中可能更强。此外,午睡可能是肥胖的一个新的独立保护因素,但需要进一步的证实性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043b/5644675/7aade34b5bfe/ofa-0006-0337-g01.jpg

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