Al-Abri Mohammed A, Al Lawati Ibtisam, Al Zadjali Fahad
Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Department of Physiology, Oman College of Health Sciences, Muscat, Oman.
Front Psychiatry. 2022 Oct 10;13:869464. doi: 10.3389/fpsyt.2022.869464. eCollection 2022.
Sleep has different patterns followed worldwide and can be influenced by social, cultural, and environmental factors. Daytime napping is commonly practiced in different parts of the world with controversial results of its effect on glucose metabolism. The current study aims to examine the association of afternoon napping and night sleep duration with metabolic derangements.
This is a cross-sectional study involving young adults and middle-aged subjects. Anthropometric measurements were taken for height and weight and hip and waist ratio. Consented subjects were asked to wear actigraphy for 1 week and run their usual daily activities. Home sleep apnea testing was performed to exclude obstructive sleep apnea. Subjects had been asked to come fasting on day seven for blood collection to test for fasting glucose, glycated hemoglobin, lipid profile, and insulin.
A total of 405 subjects were involved to complete the study (52% male, 48% female). The mean age of participants was 32.8 ± 11.5 years. The study indicated that the duration of afternoon napping was significantly associated with abnormal glycated hemoglobin (HbA1c > 5.7%) ( = 0.01) and body mass index ( = 0.046) independent of age, gender, and nocturnal sleep duration. Nocturnal sleep duration was associated with increased insulin level ( = 0.04).
Afternoon napping is associated with an increased level of glycated hemoglobin and obesity and that may predispose to the development of type 2 diabetes mellitus.
睡眠模式在全球各地各不相同，且会受到社会、文化和环境因素的影响。白天小睡在世界不同地区普遍存在，但其对葡萄糖代谢的影响结果存在争议。本研究旨在探讨午睡时间和夜间睡眠时间与代谢紊乱之间的关联。
这是一项涉及年轻人和中年受试者的横断面研究。测量了身高、体重、臀围和腰围等人体测量数据。同意参与的受试者被要求佩戴活动记录仪1周，并进行日常活动。进行了家庭睡眠呼吸暂停测试以排除阻塞性睡眠呼吸暂停。要求受试者在第7天空腹前来采血，以检测空腹血糖、糖化血红蛋白、血脂和胰岛素。
共有405名受试者参与完成了该研究（男性占52%，女性占48%）。参与者的平均年龄为32.8±11.5岁。研究表明，午睡时间与糖化血红蛋白异常（HbA1c>5.7%）（P=0.01）和体重指数（P=0.046）显著相关，且不受年龄、性别和夜间睡眠时间的影响。夜间睡眠时间与胰岛素水平升高相关（P=0.04）。
午睡与糖化血红蛋白水平升高和肥胖有关，这可能易导致2型糖尿病的发生。
