Shaaban Hamid, Layne Trevor, Sensakovic John W, Boghossian Jack
Department of Infectious Diseases, Hematology and Oncology, St Michael's Medical Center, Newark, USA.
Int J STD AIDS. 2014 Feb;25(2):152-4. doi: 10.1177/0956462413496080. Epub 2013 Jul 19.
Acute respiratory distress syndrome (ARDS) is a serious complication of sepsis. Only a few cases of non-tuberculous mycobacteria complicated by ARDS have been discussed in the literature to date. Mycobacterium kansasii is the most pathogenic non-tuberculous mycobacterium affecting the lung. In the late stages of acquired immunodeficiency syndrome (AIDS), it may also present as disseminated disease. The clinical course is usually chronic, and the time to clinical diagnosis can sometimes be long, requiring a careful and meticulous search for the pathogen. To our knowledge, this is the first case report of disseminated M. kansasii infection complicated by ARDS and acute liver failure in a patient with end-stage AIDS.
急性呼吸窘迫综合征（ARDS）是脓毒症的一种严重并发症。迄今为止，文献中仅讨论了少数几例非结核分枝杆菌合并ARDS的病例。堪萨斯分枝杆菌是最具致病性的影响肺部的非结核分枝杆菌。在获得性免疫缺陷综合征（AIDS）晚期，它也可能表现为播散性疾病。临床病程通常为慢性，临床诊断时间有时可能较长，需要仔细且细致地寻找病原体。据我们所知，这是首例关于晚期艾滋病患者播散性堪萨斯分枝杆菌感染合并ARDS和急性肝衰竭的病例报告。
