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肩胛上神经阻滞治疗脑卒中后 1 年内肩部疼痛:一项随机对照试验。

Suprascapular nerve block for shoulder pain in the first year after stroke: a randomized controlled trial.

机构信息

From the Department of Rehabilitation and Aged Care (Z.A.-W., M.C.) and Department of Rheumatology (E.M.S.), Flinders University, Daw Park, South Australia.

出版信息

Stroke. 2013 Nov;44(11):3136-41. doi: 10.1161/STROKEAHA.113.002471. Epub 2013 Aug 22.

Abstract

BACKGROUND AND PURPOSE

Shoulder pain is a common complication after stroke that can impede participation in rehabilitation and has been associated with poorer outcomes. Evidence-based treatments for hemiplegic shoulder pain are limited. Suprascapular nerve block (SSNB) is a safe and effective treatment of shoulder pain associated with arthritic shoulder conditions, but its usefulness in a stroke population is unclear.

METHODS

We undertook a randomized controlled trial assessing the effectiveness of SSNB in a population of 64 stroke patients (onset < 1 year) with hemiplegic shoulder pain. The primary outcome was pain measured on a visual analogue scale (VAS). Secondary outcomes were disability (Modified Rankin Scale, Croft Disability Index) and quality of life (EuroQol Health Questionnaire). All participants were assessed before randomization, and at 1, 4, and 12 weeks postintervention. Both groups continued with routine therapy.

RESULTS

Although both intervention and control groups demonstrated reduction in pain score, participants who received SSNB consistently demonstrated superior, statistically significant pain reduction compared with placebo. Mean VAS reduction in the SSNB group was >18 mm greater than participants receiving placebo injection. The number needed to treat with SSNB to reduce 1 stroke survivor's pain by 50% at 4 weeks is 4. No significant differences in function or quality of life were observed. No adverse events were reported.

CONCLUSIONS

Suprascapular nerve block is a safe and effective treatment for patients with hemiplegic shoulder pain.

CLINICAL TRIAL REGISTRATION URL

http://www.anzctr.org.au. Unique identifier: ACTRN12609000621213.

摘要

背景与目的

肩部疼痛是中风后的常见并发症,会妨碍康复参与,并与较差的预后相关。针对偏瘫性肩部疼痛的循证治疗方法有限。肩胛上神经阻滞(SSNB)是一种安全有效的治疗方法,适用于与关节炎性肩部疾病相关的肩部疼痛,但在中风患者中的应用效果尚不清楚。

方法

我们进行了一项随机对照试验,评估了肩胛上神经阻滞(SSNB)在 64 名中风后(发病<1 年)偏瘫性肩部疼痛患者中的有效性。主要结局是视觉模拟量表(VAS)上的疼痛测量值。次要结局是残疾(改良 Rankin 量表、Croft 残疾指数)和生活质量(EuroQol 健康问卷)。所有参与者在随机分组前、干预后 1、4 和 12 周进行评估。两组均继续接受常规治疗。

结果

尽管干预组和对照组的疼痛评分均有所降低,但接受 SSNB 治疗的患者的疼痛缓解程度始终优于安慰剂组,具有统计学意义。SSNB 组的 VAS 平均降低幅度比接受安慰剂注射的患者高 18 毫米以上。在 4 周时,SSNB 治疗减少 1 名中风幸存者疼痛 50%的治疗需要数为 4。未观察到功能或生活质量的显著差异。未报告不良事件。

结论

肩胛上神经阻滞是治疗偏瘫性肩部疼痛患者的一种安全有效的方法。

临床试验注册网址

http://www.anzctr.org.au。独特标识符:ACTRN12609000621213。

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