Sadrnia Saeid, Pourmoghaddas Masoud, Hadizadeh Mahmoud, Maghamimehr Asiyeh, Esmaeeli Masoumeh, Amirpour Afshin, Khosravi Alireza
Assistant Professor, Arak University of Medical Sciences, Arak, Iran.
ARYA Atheroscler. 2013 Jun;9(4):241-6.
Primary percutaneous coronary intervention (PCI) is the main treatment for patients with ST-segment elevation myocardial infarction (STEMI). We investigated factors affecting the major complications of this procedure.
This case-control study assessed 200 patients receiving primary PCI for STEMI. Effects of some factors including age, sex, coronary artery risk factors, left ventricular function, thrombolysis in myocardial infarction (TIMI) flow, and number of involved vessels on major adverse cardiac events (MACE) were studied.
Two thirds of patients were male but sex had no significant effect on MACE. Similarly, age, hypertension, and hyperlipidemia did not significantly affect the incidence of MACE. However, Killip class, left ventricular ejection fraction, diabetes, TIMI flow, and type of involved vessels had significant relations with the incidence of MACE.
According to our findings, factors such as diabetes, left ventricular function, left anterior descending artery involvement, and low TIMI flow are risk factors of MACE.
直接经皮冠状动脉介入治疗（PCI）是ST段抬高型心肌梗死（STEMI）患者的主要治疗方法。我们研究了影响该手术主要并发症的因素。
本病例对照研究评估了200例接受直接PCI治疗的STEMI患者。研究了年龄、性别、冠状动脉危险因素、左心室功能、心肌梗死溶栓（TIMI）血流以及受累血管数量等因素对主要不良心脏事件（MACE）的影响。
三分之二的患者为男性，但性别对MACE无显著影响。同样，年龄、高血压和高脂血症对MACE的发生率也无显著影响。然而，Killip分级、左心室射血分数、糖尿病、TIMI血流以及受累血管类型与MACE的发生率有显著关系。
根据我们的研究结果，糖尿病、左心室功能、左前降支受累以及TIMI血流低等因素是MACE的危险因素。
