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[大鼠大网膜乳斑在炎症中的形态学特征]

[Morphological features of milky spots of the rat omentum in inflammation].

作者信息

Kremli S M, Mamontov S G

出版信息

Biull Eksp Biol Med. 1990 Jun;109(6):616-9.

PMID:2397311
Abstract

The omental milky sports of the rat have been examined with the light and electron microscope after intraperitoneal stimulation by particulate coal and zymosan. No positive correlation between cell level proliferation in milky spots and alteration of their size has been found. The increase in size of milky spots is due to the inflow of cells from the blood and bone marrow. The development in milky spots of a great number of macrophages "tubercles" and multinucleated giant cells in the experimental conditions may respond to inflammation. The administration of zymosan result in the influx of lymphocytes forming lymphatic follicle-like structure. Despite the absence of germinative centres, the appearance of a great number of lymphoblasts and plasma cells in the milky spots provides the evidence of the active antibody production aimed at immunological protection of abdominal cavity.

摘要

在用颗粒状煤和酵母聚糖对大鼠进行腹腔刺激后,已用光镜和电镜对大鼠的网膜乳斑进行了检查。未发现乳斑中细胞水平的增殖与其大小改变之间存在正相关。乳斑大小的增加是由于血液和骨髓中的细胞流入所致。在实验条件下,乳斑中大量巨噬细胞“结节”和多核巨细胞的形成可能是对炎症的反应。给予酵母聚糖会导致淋巴细胞流入,形成淋巴滤泡样结构。尽管没有生发中心,但乳斑中出现大量淋巴母细胞和浆细胞,这为旨在对腹腔进行免疫保护的活跃抗体产生提供了证据。

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