Mandache E, Moldoveanu E, Savi G
Morphol Embryol (Bucur). 1985 Apr-Jun;31(2):137-42.
The investigation has been carried out on stimulated and unstimulated peritoneal cavities of rats. China ink and Corynebacterium parvum were injected i.p. both as peritoneal stimuli and markers. Omenta were picked up at time intervals beginning with 10 min and up to seven days after the i.p. injection. The light and electronmicroscopic investigation showed after 10-30 minutes labeled macrophages stuck as monolayers on some peritoneal areas corresponding to the milky spots which developed in size and number. Days after the i.p. injection the labeled macrophages were found deeper in the milky spots. After the fourth day they appeared in the regional lymph nodes. The milky spots contained also large lymphocytes and plasma cells. The results suggest that milky spots are not only places of resident macrophages development and release in the peritoneal cavity but also their exit pathways. Therefore the omentum leads the traffic of peritoneal macrophages. The developed milky spots play also the role of lymphoid structures providing grounds for macrophage-lymphocyte contacts.
已对大鼠受刺激和未受刺激的腹腔进行了研究。将中国墨汁和短小棒状杆菌经腹腔注射，作为腹腔刺激物和标记物。在腹腔注射后10分钟开始，每隔一段时间直至七天，摘取大网膜。光学显微镜和电子显微镜研究显示，10 - 30分钟后，标记的巨噬细胞以单层形式附着在一些与乳斑相对应的腹腔区域，乳斑的大小和数量不断增加。腹腔注射数天后，在乳斑深处发现了标记的巨噬细胞。第四天之后，它们出现在局部淋巴结中。乳斑中还含有大量淋巴细胞和浆细胞。结果表明，乳斑不仅是腹腔中常驻巨噬细胞发育和释放的场所，也是它们的排出途径。因此，大网膜引导着腹腔巨噬细胞的运输。发育成熟的乳斑还起到淋巴结构的作用，为巨噬细胞 - 淋巴细胞接触提供场所。
