Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University, Marchioninistr. 15, 81377, Munich, Germany,
Eur Arch Otorhinolaryngol. 2014 May;271(5):1051-5. doi: 10.1007/s00405-013-2660-4. Epub 2013 Aug 22.
The squamous cell carcinoma of the nasal vestibule (SCCNV) is a comparatively rare malignant disease. It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, however some recent reports have suggested that early stage tumors are equally or even more effectively managed by surgery. There was no standardized surgical procedure applied in these studies, though. The goal of our investigation was the retrospective evaluation of patients with a T1 or T2 carcinoma of the nasal vestibule who were treated surgically with an endonasal, endoscope-controlled approach at our ENT clinic between 2008 and 2010. Given the rarity of SCCNV, the 10 included cases represent the largest group of patients with early stage SCCNV treated primarily surgically by an endonasal approach so far. Our study shows that the endonasal resection of an early stage vestibular carcinoma seems adequate as a possible therapy. In the follow-up observation period no local or loco-regional recurrence was observed. The external cosmetic damage and endonasal scarring do not appear to be pronounced even following cartilage resection and were regarded as not seriously disadvantageous.
鼻腔前庭鳞状细胞癌（SCCNV）是一种相对罕见的恶性疾病。它发生在鼻阈的过渡区。对于小肿瘤的治疗选择存在争议。由于更好的美容效果，通常推荐放射治疗，但是最近的一些报告表明，手术同样可以甚至更有效地治疗早期肿瘤。然而，在这些研究中，没有应用标准化的手术程序。我们的研究目的是回顾性评估 2008 年至 2010 年间在我们的耳鼻喉科诊所接受经鼻内窥镜控制的鼻腔前庭内外科治疗的 T1 或 T2 期鼻腔前庭癌患者。由于 SCCNV 的罕见性，这 10 例包括了迄今为止通过经鼻内窥镜治疗的早期 SCCNV 患者中最大的一组病例。我们的研究表明，早期前庭癌的经鼻切除术作为一种可能的治疗方法是足够的。在随访观察期间，没有观察到局部或局部复发。即使在切除软骨后，外部美容损伤和经鼻瘢痕似乎也不明显，被认为没有严重的不利影响。
