Weinberger J M, Briant T D, Cummings B J, Wong C S
E.N.T./Head and Neck Tumor Site Group, Princess Margaret Hospital, Toronto, Ontario, Canada.
J Otolaryngol. 1988 Dec;17(7):372-5.
A retrospective analysis of 61 patients who were treated for squamous cell carcinoma of the nasal vestibule is presented. The general policy was to treat these carcinomas with radiation therapy, in view of the perception that this leads to a more acceptable cosmetic result. The primary nasal carcinoma was treated by surgery in five patients and by radiation in 56 patients. Surgical salvage of recurrent carcinoma in the nasal vestibule was performed without complications in 12 patients and resulted in local control in seven. Regional node metastases present at the time of diagnosis in two patients were not controlled by combined radiation and surgery. Late-developing regional node metastases were successfully managed by node dissection in three of four patients. The policy of initial treatment of the primary tumor by radiation, reserving surgery for the management of residual or metastatic cancer, resulted in good control rates and cosmesis.
本文对61例鼻前庭鳞状细胞癌患者进行了回顾性分析。鉴于放疗能带来更可接受的美容效果,总体治疗策略是采用放射治疗这些癌症。5例原发性鼻癌患者接受了手术治疗,56例接受了放射治疗。12例鼻前庭复发性癌患者接受了手术挽救,无并发症发生,7例实现了局部控制。2例诊断时出现的区域淋巴结转移患者,联合放疗和手术未能控制病情。4例患者中有三例通过淋巴结清扫成功处理了晚期出现的区域淋巴结转移。对原发性肿瘤采用放疗作为初始治疗方法,保留手术用于处理残留或转移性癌症,取得了良好的控制率和美容效果。