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手术在鼻前庭鳞状细胞癌治疗中的作用。

The role of surgery in the treatment of squamous cell carcinoma of the nasal vestibule.

作者信息

Weinberger J M, Briant T D, Cummings B J, Wong C S

机构信息

E.N.T./Head and Neck Tumor Site Group, Princess Margaret Hospital, Toronto, Ontario, Canada.

出版信息

J Otolaryngol. 1988 Dec;17(7):372-5.

PMID:3230610
Abstract

A retrospective analysis of 61 patients who were treated for squamous cell carcinoma of the nasal vestibule is presented. The general policy was to treat these carcinomas with radiation therapy, in view of the perception that this leads to a more acceptable cosmetic result. The primary nasal carcinoma was treated by surgery in five patients and by radiation in 56 patients. Surgical salvage of recurrent carcinoma in the nasal vestibule was performed without complications in 12 patients and resulted in local control in seven. Regional node metastases present at the time of diagnosis in two patients were not controlled by combined radiation and surgery. Late-developing regional node metastases were successfully managed by node dissection in three of four patients. The policy of initial treatment of the primary tumor by radiation, reserving surgery for the management of residual or metastatic cancer, resulted in good control rates and cosmesis.

摘要

本文对61例鼻前庭鳞状细胞癌患者进行了回顾性分析。鉴于放疗能带来更可接受的美容效果,总体治疗策略是采用放射治疗这些癌症。5例原发性鼻癌患者接受了手术治疗,56例接受了放射治疗。12例鼻前庭复发性癌患者接受了手术挽救,无并发症发生,7例实现了局部控制。2例诊断时出现的区域淋巴结转移患者,联合放疗和手术未能控制病情。4例患者中有三例通过淋巴结清扫成功处理了晚期出现的区域淋巴结转移。对原发性肿瘤采用放疗作为初始治疗方法,保留手术用于处理残留或转移性癌症,取得了良好的控制率和美容效果。

相似文献

1
The role of surgery in the treatment of squamous cell carcinoma of the nasal vestibule.手术在鼻前庭鳞状细胞癌治疗中的作用。
J Otolaryngol. 1988 Dec;17(7):372-5.
2
Squamous cell carcinoma of the nasal vestibule.鼻前庭鳞状细胞癌。
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Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting--the MSKCC experience.现代放疗技术用于鼻腔及鼻窦癌术后治疗——纪念斯隆凯特琳癌症中心的经验
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The influence of lymph node metastasis in the treatment of squamous cell carcinoma of the oral cavity, oropharynx, larynx, and hypopharynx: N0 versus N+.淋巴结转移对口腔、口咽、喉和下咽鳞状细胞癌治疗的影响:N0与N+的对比
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Radiotherapy for squamous cell carcinoma of the nasal cavity.鼻腔鳞状细胞癌的放射治疗
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Delayed regional metastases, distant metastases, and second primary malignancies in squamous cell carcinomas of the larynx and hypopharynx.喉和下咽鳞状细胞癌的区域转移延迟、远处转移及第二原发性恶性肿瘤
Laryngoscope. 2001 Jun;111(6):1079-87. doi: 10.1097/00005537-200106000-00028.
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Radiotherapy for squamous cell carcinoma of the nasal vestibule.鼻前庭鳞状细胞癌的放射治疗
Am J Clin Oncol. 2007 Dec;30(6):612-6. doi: 10.1097/COC.0b013e31815aff1f.

引用本文的文献

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Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report.西米普利单抗有效治疗鼻前庭鳞状细胞癌:一例报告
Case Rep Oncol. 2023 Sep 19;16(1):935-938. doi: 10.1159/000531843. eCollection 2023 Jan-Dec.
2
The presence of aberrant p53 pattern is a negative prognostic predictor in squamous cell carcinoma of the nasal vestibule.异常p53模式的存在是鼻前庭鳞状细胞癌的一个负面预后预测指标。
Eur Arch Otorhinolaryngol. 2017 Sep;274(9):3503-3512. doi: 10.1007/s00405-017-4659-8. Epub 2017 Jul 1.
3
Local control and intermediate-term cosmetic outcome following IMRT for nasal tumors : An update.
调强放射治疗后鼻腔肿瘤的局部控制和中期美容效果:最新进展
Strahlenther Onkol. 2017 Apr;193(4):295-304. doi: 10.1007/s00066-016-1083-8. Epub 2016 Dec 5.