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[重症监护病房中的心房颤动。独特的实体——特殊治疗?]

[Atrial fibrillation in the ICU. Distinct entity--special treatment?].

作者信息

Heinz G

机构信息

Abteilung für Kardiologie, Intensivstation 13H3, Universitätsklinik für Innere Medizin II, Währinger Gürtel 18-20, 1090, Wien, Österreich,

出版信息

Med Klin Intensivmed Notfmed. 2013 Oct;108(7):549-54. doi: 10.1007/s00063-012-0141-y. Epub 2013 Aug 24.

DOI:10.1007/s00063-012-0141-y
PMID:23974648
Abstract

Atrial fibrillation (AF) is the single most frequent arrhythmia in the intensive care unit, occurring among 44-61 % of all patients with arrhythmias in the intensive care unit. The success rate of electrical cardioversion (DC-CV) early after surgery is as low as 10-35 % in postoperative AF but 6 weeks after discharge 90 % are in sinus rhythm (SR). Several guidelines recommend rate control in these patients and rate control with β-blockers and calcium channel blockers is not inferior with respect to outcome, 6 min walk test, and quality of life. DC-CV is recommended in unstable and heart failure patients. The term resistant AF is suggested for that distinct situation of AF not amenable to cardioversion solely in the acute phase of critical illness.

摘要

心房颤动(AF)是重症监护病房中最常见的心律失常,在所有重症监护病房心律失常患者中占44%-61%。术后早期电复律(DC-CV)在术后房颤中的成功率低至10%-35%,但出院6周后90%的患者恢复窦性心律(SR)。多项指南建议对这些患者进行心率控制,使用β受体阻滞剂和钙通道阻滞剂进行心率控制在结局、6分钟步行试验和生活质量方面并不逊色。不稳定和心力衰竭患者建议进行DC-CV。“难治性房颤”一词用于指仅在危重症急性期不适合复律的房颤这种特殊情况。

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Crit Care. 2013 Apr 19;17(2):133. doi: 10.1186/cc12602.
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Management of patients with atrial fibrillation (compilation of 2006 ACCF/AHA/ESC and 2011 ACCF/AHA/HRS recommendations): a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines.心房颤动患者的管理(2006年美国心脏病学会基金会/美国心脏协会/欧洲心脏病学会及2011年美国心脏病学会基金会/美国心脏协会/心律学会推荐意见汇编):美国心脏病学会/美国心脏协会实践指南工作组报告
Circulation. 2013 May 7;127(18):1916-26. doi: 10.1161/CIR.0b013e318290826d. Epub 2013 Apr 1.
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Bioactivity of enoxaparin in critically ill patients with normal renal function.
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Br J Clin Pharmacol. 2012 Nov;74(5):806-14. doi: 10.1111/j.1365-2125.2012.04285.x.
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Comparison of effectiveness and safety of ranolazine versus amiodarone for preventing atrial fibrillation after coronary artery bypass grafting.比较雷诺嗪与胺碘酮预防冠状动脉旁路移植术后心房颤动的有效性和安全性。
Am J Cardiol. 2011 Sep 1;108(5):673-6. doi: 10.1016/j.amjcard.2011.04.017. Epub 2011 Jul 2.
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A randomized active-controlled study comparing the efficacy and safety of vernakalant to amiodarone in recent-onset atrial fibrillation.一项比较维纳卡兰与胺碘酮在新发心房颤动中疗效和安全性的随机、活性对照研究。
J Am Coll Cardiol. 2011 Jan 18;57(3):313-21. doi: 10.1016/j.jacc.2010.07.046.
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Usefulness of vernakalant hydrochloride injection for rapid conversion of atrial fibrillation.盐酸维纳卡兰注射液在心房颤动快速转复中的应用
Am J Cardiol. 2010 Nov 1;106(9):1277-83. doi: 10.1016/j.amjcard.2010.06.054.
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Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).心房颤动管理指南:欧洲心脏病学会(ESC)心房颤动管理特别工作组
Eur Heart J. 2010 Oct;31(19):2369-429. doi: 10.1093/eurheartj/ehq278. Epub 2010 Aug 29.
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Am Heart J. 2010 Jun;159(6):1095-101. doi: 10.1016/j.ahj.2010.02.035.
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Circ Arrhythm Electrophysiol. 2009 Dec;2(6):652-9. doi: 10.1161/CIRCEP.109.870204.
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Crit Care Med. 2009 Jul;37(7):2174-9; quiz 2180. doi: 10.1097/CCM.0b013e3181a02f56.