Nwachokor F N, Forae G C
Department of Pathology, University of Benin Teaching Hospital, Benin City, Nigeria.
Niger J Clin Pract. 2013 Oct-Dec;16(4):429-32. doi: 10.4103/1119-3077.116883.
The uterine cervix is a gateway to several non-neoplastic and neoplastic gynecological lesions. Most of these non-neoplastic lesions are commonly found in women of reproductive age. These lesions constitute a source of morbidity and mortality in women worldwide hence the need to analyze them to provide a baseline data of the pattern of these lesions in our local environment.
The purpose of this study is to determine the frequency and morphological patterns of non-neoplastic cervical lesions at the central hospital, Warri, Nigeria.
All uterine cervical biopsies received at the Department of Pathology, Central Hospital, Warri over a 7 year period (January 2005-December 2011) were the specimens for this study. Slides were retrieved from the archives of the Department of Pathology. Where necessary, new sections were made from formalin fixed, paraffin embedded blocks.
A total of 176 cervical specimens were received in the Pathology Department during this period. Of these, 56.3% were benign lesions while 43.7% were malignant. Among the benign cases, non-neoplastic lesions accounted for 92.9% of benign cervical lesions. The age range of non-neoplastic cervical lesions was 20 to 89 years with a mean age of 54.9 ± 4.6 years. The peak age incidence of non-neoplastic cervical lesion was 40-49 years which accounted for 33.7%. Inflammatory lesions and tumor-like lesions accounted for 59.8% and 40.2% of non-neoplastic cervical lesions respectively. Among the inflammatory lesions, chronic non-specific cervicitis was the most commonly encountered lesion constituting 72.2% of all inflammation. Human papilloma virus (HPV) cervicitis with koilocytic changes accounted for 14.5% of all inflammatory lesions.
Inflammatory lesions were the most frequent non-neoplastic cervical lesions. These lesions therefore account for significant amount of gynecological problems in our environment. Adequate cervical screening with follow up histological biopsies is a relevant tool in diagnosing them to enhance early detection of premalignant and malignant cervical lesions.
子宫颈是多种非肿瘤性和肿瘤性妇科病变的通道。这些非肿瘤性病变大多常见于育龄女性。这些病变是全球女性发病和死亡的一个来源，因此有必要对其进行分析，以提供我们当地环境中这些病变模式的基线数据。
本研究的目的是确定尼日利亚瓦里中央医院非肿瘤性宫颈病变的频率和形态学模式。
本研究的标本为瓦里中央医院病理科在7年期间（2005年1月至2011年12月）接收的所有子宫颈活检组织。玻片从病理科档案中检索。必要时，从福尔马林固定、石蜡包埋的组织块制作新切片。
在此期间，病理科共接收176例宫颈标本。其中，56.3%为良性病变，43.7%为恶性病变。在良性病例中，非肿瘤性病变占良性宫颈病变的92.9%。非肿瘤性宫颈病变的年龄范围为20至89岁，平均年龄为54.9±4.6岁。非肿瘤性宫颈病变的发病高峰年龄为40 - 49岁，占33.7%。炎症性病变和肿瘤样病变分别占非肿瘤性宫颈病变的59.8%和40.2%。在炎症性病变中，慢性非特异性宫颈炎是最常见的病变，占所有炎症的72.2%。伴有挖空细胞改变的人乳头瘤病毒（HPV）宫颈炎占所有炎症性病变的14.5%。
炎症性病变是最常见的非肿瘤性宫颈病变。因此，这些病变在我们的环境中导致了大量的妇科问题。进行充分的宫颈筛查并进行后续组织学活检是诊断这些病变以提高宫颈前恶性病变和恶性病变早期检测的相关工具。
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