Rocha Luiza F, Marangoni Roberta G, Sampaio-Barros Percival D, Levy-Neto Mauricio, Yoshinari Natalino H, Bonfa Eloisa, Steen Virginia, Kowalski Sergio C
Disciplina de Reumatologia, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Arnaldo, 455 - 3º, Andar, Cerqueira César, São Paulo, São Paulo, Brazil, 01246-903.
Clin Rheumatol. 2014 May;33(5):699-706. doi: 10.1007/s10067-013-2370-8. Epub 2013 Aug 22.
The Scleroderma Health Assessment Questionnaire (SHAQ) is a feasible multisystem specific tool that has been extensively used as an additional assessment for systemic sclerosis (SSc). The aim of this study is to cross-culturally adapt and validate the Brazilian version of the SHAQ. Construct validity was assessed based on the correlations between SHAQ and both the Medical Outcomes Survey Short Form 36 version 2 (SF-36v2™) and the Health Assessment Questionnaire Disability Index (HAQ-DI). The correlation between the SHAQ and disease severity was assessed by Spearman's correlation coefficient. The reproducibility of the SHAQ was evaluated by the intraclass correlation coefficient (ICC). Among the 151 consecutive outpatients evaluated, 59 % had limited SSc subtype. The overall disease severity visual analog scale (VAS) of the SHAQ was statistically significantly correlated to HAQ-DI, pain VAS, and the SF-36v2™ physical component summary score (r = 0.595, r = 0.612, and r = -0.582, respectively; p < 0.001). Further analysis of all SF-36v2™ components revealed statistically significant correlations between overall disease severity VAS and bodily pain (r = -0.621, p < 0.001), vitality (r = -0.544, p < 0.001), physical function (r = -0.510, p < 0.001), and role limitation-physical dimensions (r = -0.505, p < 0.001). Moreover, digestive, pulmonary, and overall disease severity VASs were statistically significantly correlated to the number of organs involved (r = 0.178, p = 0.029; r = 0.214, p = 0.008; r = 0.282, p < 0.001). We also demonstrated high reproducibility for SHAQ (ICC = 0.757, 95 % confidence interval = 0.636-0.842). The Brazilian version of the SHAQ demonstrated both construct and discriminant validities as well as good reproducibility.
硬皮病健康评估问卷（SHAQ）是一种可行的多系统特异性工具，已被广泛用作系统性硬化症（SSc）的附加评估工具。本研究的目的是对巴西版SHAQ进行跨文化调适和验证。基于SHAQ与医学结局调查简表36第2版（SF - 36v2™）以及健康评估问卷残疾指数（HAQ - DI）之间的相关性评估结构效度。通过Spearman相关系数评估SHAQ与疾病严重程度之间的相关性。通过组内相关系数（ICC）评估SHAQ的可重复性。在连续评估的151名门诊患者中，59%为局限性硬皮病亚型。SHAQ的总体疾病严重程度视觉模拟量表（VAS）与HAQ - DI、疼痛VAS以及SF - 36v2™身体成分汇总得分在统计学上显著相关（分别为r = 0.595、r = 0.612和r = -0.582；p < 0.001）。对所有SF - 36v2™成分的进一步分析显示，总体疾病严重程度VAS与身体疼痛（r = -0.621，p < 0.001）、活力（r = -0.544，p < 0.001）、身体功能（r = -0.510，p < 0.001）以及角色限制 - 身体维度（r = -0.505，p < 0.001）之间存在统计学显著相关性。此外，消化系统、肺部和总体疾病严重程度VAS与受累器官数量在统计学上显著相关（r = 0.178，p = 0.029；r = 0.214，p = 0.008；r = 0.282，p < 0.001）。我们还证明了SHAQ具有高可重复性（ICC = 0.757，95%置信区间 = 0.636 - 0.842）。巴西版SHAQ显示出结构效度和区分效度以及良好的可重复性。
