Department of Orthopedics, General Hospital of Shenyang Military Area Command of Chinese PLA, Shenyang, Liaoning, 110016 , China.
Acta Neurochir (Wien). 2013 Oct;155(10):1931-6. doi: 10.1007/s00701-013-1828-4. Epub 2013 Aug 22.
The optimal timing for percutaneous endoscopic lumbar discectomy (PELD) in cases of lumbar disc herniation (LDH) is debatable. This retrospective study sought to determine which category of PELD surgical intervention time resulted in greater improvement in clinical outcomes.
We retrospectively reviewed the medical records of 145 patients who underwent PELD for single-level LDH. The patients were divided into three categories according to the duration of leg pain before surgery, the early and late group being symptomatic for ≤3 months and >3 months, ≤6 months and >6 months, ≤12 months and >12 months. Surgical time, blood loss, postoperative hospital stay, hospitalization cost, rates of reoperation due to surgical failure, Macnab criteria assessment, visual analogue scale (VAS) of back pain, leg pain and numbness, Japanese orthopedic association low back pain score (JOA) before and after surgery were compared.
No significant differences were found between the early and late groups according to different categories in patients' demographics, surgical time, blood loss, preoperative and postoperative VAS (lower-back pain, leg pain and numbness) scores, JOA scores and distribution of Macnab criteria assessment. Early PELD surgical intervention did not result in greater improvement of clinical outcomes. Later surgical intervention resulted in about one-third surgical failure rates for patients being symptomatic for >6 months (≤6 months, 11/96, 11.5 %; >6 months, 2/49, 4.1 %; P = 0.245) and >12 months (≤12 months, 12/120, 10.0 %; >12 months, 1/25, 4.0 %; P = 0.568) of the early surgical intervention groups. Significant difference was observed between the comorbidities and non-comorbidities group in the rate of reoperation (P = 0.040).
Early PELD surgical intervention did not result in greater improvement of clinical outcomes for patients with lumbar disc herniation. Later surgical intervention resulted in less failure rates for patients than the early surgical intervention groups. PELD performed when the leg pain before surgery being symptomatic for >6 months may be good for avoiding surgical failure and reducing the duration of leg pain.
腰椎间盘突出症(LDH)患者行经皮内镜腰椎间盘切除术(PELD)的最佳时机仍存在争议。本回顾性研究旨在确定哪种 PELD 手术干预时间类别可带来更大的临床疗效改善。
我们回顾性分析了 145 例行单节段 LDH 行 PELD 治疗的患者的病历资料。根据术前腿痛持续时间,将患者分为三组,早期和晚期组腿痛症状分别为≤3 个月和>3 个月、≤6 个月和>6 个月、≤12 个月和>12 个月。比较手术时间、出血量、术后住院时间、住院费用、因手术失败而再次手术的比率、Macnab 标准评估、视觉模拟量表(VAS)评分(腰背疼痛、腿痛和麻木)、手术前后日本骨科协会腰痛评分(JOA)。
根据不同分组,早期和晚期组患者的一般资料、手术时间、出血量、术前和术后 VAS(腰背疼痛、腿痛和麻木)评分、JOA 评分以及 Macnab 标准评估分布均无显著差异。早期 PELD 手术干预并未带来更大的临床疗效改善。对于腿痛症状持续>6 个月(≤6 个月,11/96,11.5%;>6 个月,2/49,4.1%;P=0.245)和>12 个月(≤12 个月,12/120,10.0%;>12 个月,1/25,4.0%;P=0.568)的患者,晚期手术干预的手术失败率约为早期手术干预组的三分之一。有合并症和无合并症患者的再次手术率存在显著差异(P=0.040)。
对于腰椎间盘突出症患者,早期 PELD 手术干预并未带来更大的临床疗效改善。与早期手术干预组相比,晚期手术干预的失败率更低。对于术前腿痛症状持续>6 个月的患者,行 PELD 治疗可能有助于避免手术失败和缩短腿痛持续时间。