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非常大的分子的 RNA 二级结构图谱:RNAfdl。

RNA secondary structure diagrams for very large molecules: RNAfdl.

机构信息

Centre for non-coding RNA in Technology and Health and Department of Veterinary Clinical and Animal Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark, European Molecular Biology Laboratory-Hamburg Outstation, c/o DESY, 22603 Hamburg, Germany and Centre for Bioinformatics, Institute for Biochemistry and Molecular Biology, University of Hamburg, 20146 Hamburg, Germany.

出版信息

Bioinformatics. 2013 Nov 15;29(22):2941-2. doi: 10.1093/bioinformatics/btt496. Epub 2013 Aug 23.

Abstract

SUMMARY

There are many programs that can read the secondary structure of an RNA molecule and draw a diagram, but hardly any that can cope with 10(3) bases. RNAfdl is slow but capable of producing intersection-free diagrams for ribosome-sized structures, has a graphical user interface for adjustments and produces output in common formats.

AVAILABILITY AND IMPLEMENTATION

Source code is available under the GNU General Public License v3.0 at http://sourceforge.net/projects/rnafdl for Linux and similar systems or Windows using MinGW. RNAfdl is implemented in C, uses the Cairo 2D graphics library and offers both command line and graphical user interfaces.

CONTACT

hecker@rth.dk

摘要

摘要

有许多程序可以读取 RNA 分子的二级结构并绘制图表,但几乎没有任何程序可以处理 10(3)个碱基。RNAfdl 速度较慢,但能够为核糖体大小的结构生成无交叉的图表,具有用于调整的图形用户界面,并以常见格式生成输出。

可用性和实现

源代码可在 http://sourceforge.net/projects/rnafdl 下获得,适用于 Linux 和类似系统的 GNU 通用公共许可证 v3.0 或使用 MinGW 的 Windows。RNAfdl 是用 C 语言实现的,使用 Cairo 2D 图形库,并提供命令行和图形用户界面。

联系人

hecker@rth.dk

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