Cid M C, Cervera R, Font J, Lopez-Soto A, Pallarés L, Navarro M, Ingelmo M
Department of Internal Medicine, Hospital Clínic i Provincial, Barcelona, Spain.
Clin Exp Rheumatol. 1990 Jul-Aug;8(4):359-63.
IgG and IgM isotypes of anticardiolipin (aCL) antibodies were measured in a group of 40 patients with biopsy-proven temporal arteritis (TA), 13 of them with ischemic complications related to the disease. High levels of aCL antibodies were found in only 3 (7.5%) patients. Two had high titres of both IgG and IgM isotypes and the third had high titres of the IgM isotype. No relationship between aCL antibody positivity and the development of any of the classical early occlusive complications of TA was found. However, 2 out of the 3 patients with positive aCL antibody titres later developed ischemic phenomena on conventional corticosteroid treatment. This finding suggests that aCL antibodies could perhaps have a role in the development of the late ischemic complications that occasionally occur in adequately treated TA patients.
在一组经活检证实为颞动脉炎（TA）的40例患者中检测了抗心磷脂（aCL）抗体的IgG和IgM同种型，其中13例有与该疾病相关的缺血性并发症。仅在3例（7.5%）患者中发现aCL抗体水平升高。2例患者的IgG和IgM同种型均有高滴度，第3例患者的IgM同种型有高滴度。未发现aCL抗体阳性与TA任何经典早期闭塞性并发症的发生之间存在关联。然而，3例aCL抗体滴度阳性的患者中有2例在接受常规皮质类固醇治疗后出现了缺血现象。这一发现表明，aCL抗体可能在充分治疗的TA患者偶尔发生的晚期缺血性并发症的发生中起作用。
