McHugh N J, James I E, Plant G T
Royal National Hospital for Rheumatic Diesases, Bath, England.
J Rheumatol. 1990 Jul;17(7):916-22.
IgG anticardiolipin antibodies (aCL) were found in a patient with Takayasu's arteritis and then in 11 of 22 patients with temporal arteritis (TA) studied prospectively. In comparison IgG aCL were found in only one of 18 elderly controls with rheumatoid arthritis and one of 47 healthy elderly controls. In TA IgG aCL were more frequent in those with acute disease (8/12), in those with an accompanying history of polymyalgia rheumatica (9/13), p less than 0.05); and levels normalized with corticosteroid treatment. Antineutrophil cytoplasmic antibodies (c-ANCA) were present in one patient with TA who had no systemic disease.
在一名高安动脉炎患者中发现了IgG抗心磷脂抗体（aCL），随后在22例前瞻性研究的颞动脉炎（TA）患者中的11例中也发现了该抗体。相比之下，在18例患类风湿关节炎的老年对照者中仅1例发现有IgG aCL，在47例健康老年对照者中也仅1例发现有该抗体。在TA患者中，IgG aCL在急性病患者（8/12）以及伴有风湿性多肌痛病史的患者（9/13）中更常见（p<0.05）；并且其水平在接受皮质类固醇治疗后恢复正常。1例无全身性疾病的TA患者存在抗中性粒细胞胞浆抗体（c-ANCA）。
