Dakov I, Vlasov V, Marinov V
Eksp Med Morfol. 1990;29(1):22-6.
The results from artificial pneumothorax in 25 rabbits with intrapleural administration of Uropolin (10 rabbits) as well as of 10% solution of NACl (7 rabbits) were described. Thoracotomy was made on 7th, 14th and 12 21st day and the parietal, diaphragmatic and visceral pleura with underlaying tissues were examined. Proliferation of the mesothelium [correction of mesother] and growth of the connective tissue, which were more manifested in rabbits treated with Uropolin, were established histologically. The authors think that pathohistological examinations confirm the clinical observed favourable effect of intrapleural administration of Uropolin for obliteration of the pleural cavity.
描述了对25只家兔进行人工气胸的结果，其中10只家兔经胸膜腔内注射尿促性素，7只家兔经胸膜腔内注射10%氯化钠溶液。在第7天、第14天和第21天进行开胸手术，并检查壁层、膈层和脏层胸膜及其下方组织。组织学检查发现，间皮细胞[纠正为间皮]增殖和结缔组织生长，在接受尿促性素治疗的家兔中表现更为明显。作者认为，病理组织学检查证实了临床观察到的胸膜腔内注射尿促性素对胸膜腔闭塞的良好效果。
