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弓部手术中的脑保护最佳策略——顺行性选择性脑灌注和充分低温。

Best strategy for cerebral protection in arch surgery - antegrade selective cerebral perfusion and adequate hypothermia.

机构信息

Department of Cardiac Surgery, Leipzig Heart Center - University of Leipzig, Leipzig, Germany.

出版信息

Ann Cardiothorac Surg. 2013 May;2(3):331-8. doi: 10.3978/j.issn.2225-319X.2013.02.05.

Abstract

Aortic arch surgery remains a complex surgical operation that necessitates specific neuroprotection strategies. Various approaches, such as hypothermic circulatory arrest (HCA), retrograde cerebral perfusion, and antegrade selective cerebral perfusion (aSCP), have each enjoyed periods of popularity. However, while the overall surgical approach tend to favour HCA with aSCP, technical factors, such as perfusion site, perfusate temperature and flow rate and pH management, have not been conclusively elucidated. The optimal extent of hypothermia during circulatory arrest is also unclear, particularly with recent partiality for warmer temperatures. The following perspective details the preferred surgical practice for cerebral protection in aortic arch surgery, based on existing evidence.

摘要

主动脉弓手术仍然是一项复杂的手术,需要特定的神经保护策略。各种方法,如低温循环停止(HCA)、逆行脑灌注和顺行选择性脑灌注(aSCP),都曾一度流行。然而,尽管总体手术方法倾向于支持 HCA 加 aSCP,但技术因素,如灌注部位、灌注液温度和流量以及 pH 值管理,尚未得到明确阐明。在循环停止期间,低温的最佳程度也不清楚,特别是最近对较高温度的偏爱。以下观点根据现有证据详细说明了主动脉弓手术中脑保护的首选手术实践。

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