Clark Daniel S
Ventura County Medical Center, 3291 Loma Vista Road, Ventura, CA 93003, USA.
FP Essent. 2013 Aug;411:23-7.
Peripheral artery disease (PAD) is a common vascular disease in women that is underrecognized. It is most strongly associated with smoking and diabetes. Women with PAD are more likely to have atypical or no symptoms compared with men. The classic symptoms of claudication are seen in some, but not all, patients. The most useful initial test for PAD is the ankle-brachial index. The American College of Cardiology Foundation/American Heart Association guideline recommends that it be obtained for all patients with exertional leg symptoms; patients 50 years or older with diabetes; patients 50 years or older who smoke; all patients older than 65 years; and any patient with known coronary artery disease. Other tests, such as Doppler ultrasonography, magnetic resonance angiography, and computed tomography angiography, should be reserved for patients in whom the diagnosis of PAD is unclear. Exercise programs improve symptoms. Aspirin and statins are recommended for all patients with PAD, whereas surgery is reserved for patients who do not benefit from medical therapy.
外周动脉疾病（PAD）是一种在女性中常见但未得到充分认识的血管疾病。它与吸烟和糖尿病的关联最为密切。与男性相比，患有PAD的女性更有可能出现非典型症状或无症状。一些但并非所有患者会出现间歇性跛行的典型症状。PAD最有用的初始检查是踝臂指数。美国心脏病学会基金会/美国心脏协会指南建议，对于所有有腿部运动症状的患者、50岁及以上的糖尿病患者、50岁及以上的吸烟者、所有65岁以上的患者以及任何已知患有冠状动脉疾病的患者，均应进行此项检查。其他检查，如多普勒超声检查、磁共振血管造影和计算机断层血管造影，应仅用于PAD诊断不明确的患者。运动计划可改善症状。建议所有PAD患者服用阿司匹林和他汀类药物，而手术仅适用于那些无法从药物治疗中获益的患者。
