Bunert N, Homey B, Gerber P A
Hautklinik, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Hautarzt. 2013 Oct;64(10):716-8. doi: 10.1007/s00105-013-2645-7.
A 58-year-old man presented with a two-year history of progressive onychodystrophy of the nails of both great toes. Clinical inspection as well as KOH examination and culture confirmed the diagnosis of disto-lateral onychomycosis of both nails caused by Trichophyton rubrum). The diseased nail materially was mechanically débrided. In addition both nails were treated with a 1064 nm Nd:YAG laser (spot-diameter: 5 mm; pulse-width: 0.3 ms; fluence: 12 J/cm(2); frequency: 5 Hz; impulses: 200 per toenail). The laser therapy was repeated four times at intervals of 2 months. Seven months later the patient showed complete clearance of both nails. We here demonstrate the efficacy of the Nd:YAG laser in the treatment of onychomycosis. Non-ablative laser therapy may present a promising, effective, well-tolerated and cost-efficient option for the treatment of onychomycosis. Controlled studies with relevant patient collectives are urgently needed.
一名58岁男性，双足大脚趾指甲渐进性甲营养不良已有两年病史。临床检查以及氢氧化钾检查和培养确诊为红色毛癣菌引起的双指甲远端外侧甲真菌病。对病变指甲物质进行了机械清创。此外，对双指甲均采用1064纳米掺钕钇铝石榴石激光治疗（光斑直径：5毫米；脉冲宽度：0.3毫秒；能量密度：12焦/平方厘米；频率：5赫兹；每只脚趾甲脉冲数：200次）。激光治疗每2个月重复一次，共进行了4次。7个月后，患者双指甲完全清除。我们在此证明了掺钕钇铝石榴石激光治疗甲真菌病的疗效。非剥脱性激光治疗可能是一种有前景、有效、耐受性良好且成本效益高的甲真菌病治疗选择。迫切需要对相关患者群体进行对照研究。
