Zengerling F, Müller J, Schrader A J, Schrader M
Klinik für Urologie und Kinderurologie, Universitätsklinikum Ulm, Prittwitzstraße 43, 89075, Ulm, Deutschland.
Urologe A. 2013 Sep;52(9):1265-9. doi: 10.1007/s00120-013-3319-x.
The therapy of stage I seminoma is under constant change. While surveillance, adjuvant radiotherapy and adjuvant chemotherapy were seen as equal therapeutic alternatives up to a few years ago, recently published studies make it necessary to adopt a more differentiated approach.
In this review, recent data on the long-term effects of adjuvant radiotherapy and chemotherapy, the question of risk stratification as well as the advantages and limitations of a surveillance strategy are discussed.
I期精原细胞瘤的治疗一直在不断变化。直到几年前,监测、辅助放疗和辅助化疗都被视为同等的治疗选择,但最近发表的研究使得有必要采取更具差异化的方法。
在本综述中,讨论了辅助放疗和化疗的长期影响的最新数据、风险分层问题以及监测策略的优缺点。