Theoretical and Applied Science Department, University of Insubria, Via Dunant 3, Varese, Italy,
Ecotoxicology. 2013 Oct;22(8):1255-63. doi: 10.1007/s10646-013-1113-6. Epub 2013 Aug 25.
pp'-Dichlorodiphenyl-dichloroethylene (pp'DDE), a metabolite of pp'-dichlorodiphenyl-trichloroethane poses a risk for many ecosystems in spite of the banning of the parent compound because of its persistence and bioaccumulability. Nevertheless, the knowledge of acute and chronic toxicity on aquatic organisms is still very poor. In the present study, Daphnia magna was exposed to varying concentrations of pp'DDE in water and through diet to determine both acute toxicity and potential for effects on reproduction and survivability. The 48 h IC50 was 5.08 μg L(-1) (3.76-7.01 μg L(-1)). As pp'DDE concentration in water was not stable and the amount assumed by food cannot be established with certainty, the results of chronic toxicity tests were expressed as the concentration in the organism which caused a negative effect. Grazing activity was affected with a pp'DDE concentration in the organism of 24 ng mg(-1) d.w., while the lowest observed effect concentration for fecundity reduction was 109 ng mg(-1) d.w.
对二氯二苯二氯乙烯（pp'-DDE）是对二氯二苯三氯乙烷的代谢物，尽管因其持久性和生物累积性而被禁用，但它仍然对许多生态系统构成了风险。然而，水生生物的急性和慢性毒性的相关知识仍然非常匮乏。在本研究中，通过水和食物暴露于不同浓度的 pp'-DDE 来确定大型溞的急性毒性以及对繁殖和生存能力的潜在影响。48 小时 IC50 为 5.08 μg L(-1)（3.76-7.01 μg L(-1)）。由于水中的 pp'-DDE 浓度不稳定，并且通过食物摄入的量不能确定，因此慢性毒性试验的结果表示为引起负面影响的生物体浓度。摄食活动受到生物体中 24ng mg(-1) d.w. 的 pp'-DDE 浓度的影响，而观察到的降低繁殖力的最低效应浓度为 109ng mg(-1) d.w.
