EUCAST 程序与 Etest 测定分离的念珠菌属对米卡芬净敏感性的比较。
Comparison between the EUCAST procedure and the Etest for determination of the susceptibility of Candida species isolates to micafungin.
机构信息
Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
出版信息
Antimicrob Agents Chemother. 2013 Nov;57(11):5767-70. doi: 10.1128/AAC.01032-13. Epub 2013 Aug 26.
Abstract
We compared the ability of the EUCAST EDef 7.2 and the Etest to detect the susceptibility to micafungin of 160 Candida and non-Candida clinical isolates. Agreement was higher when Etest MICs were obtained after 24 h of incubation; essential agreement was 90%, and categorical agreement was >90%. False susceptibility was seen only for Candida krusei (10%), and false resistance was observed in 6% of the isolates, ranging from 2.6% (C. glabrata) to 13% (C. albicans).
摘要
我们比较了 EUCAST EDef 7.2 和 Etest 检测 160 株念珠菌和非念珠菌临床分离株对米卡芬净敏感性的能力。孵育 24 小时后获得的 Etest MIC 时，一致性更高；基本一致率为 90%，分类一致率>90%。仅对克柔念珠菌（10%）出现假敏感性，6%的分离株出现假耐药性，范围为 2.6%（近平滑念珠菌）至 13%（白色念珠菌）。
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