青少年重症肌无力的胸腺切除术

Thymectomy in juvenile myasthenia gravis.

作者信息

Adams C, Theodorescu D, Murphy E G, Shandling B

机构信息

Division of Neurology, Hospital for Sick Children, The University of Toronto, Canada.

出版信息

J Child Neurol. 1990 Jul;5(3):215-8. doi: 10.1177/088307389000500313.

DOI:10.1177/088307389000500313

PMID:2398237

Abstract

The long-term results of thymectomy in 24 children with generalized myasthenia gravis are reviewed. Sixteen had complete remission and another seven were improved. This compares favorably with reported spontaneous remission rates of 30%. Because of the low morbidity in recent reports and the possibility that early thymectomy is more beneficial, we recommend thymectomy at the onset of juvenile generalized myasthenia gravis.

摘要

回顾了24例儿童全身型重症肌无力患者胸腺切除的长期结果。16例完全缓解，另有7例病情改善。这与报道的30%的自发缓解率相比更具优势。鉴于近期报道中胸腺切除的低发病率以及早期胸腺切除可能更有益的可能性，我们建议在青少年全身型重症肌无力发病时即行胸腺切除术。