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脑死亡创伤患者的器官获取与储存:我们在一级创伤中心的经验及当前观点。

Organ retrieval and banking in brain dead trauma patients: Our experience at level-1 trauma centre and current views.

作者信息

Sawhney Chhavi, Kaur Manpreet, Lalwani Sanjeev, Gupta Babita, Balakrishnan Ira, Vij Aarti

机构信息

Department of Anaesthesia and Critical Care, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Anaesth. 2013 May;57(3):241-7. doi: 10.4103/0019-5049.115599.

DOI:10.4103/0019-5049.115599
PMID:23983281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3748677/
Abstract

BACKGROUND

Organ retrieval from brain dead patients is getting an increased attention as the waiting list for organ recipients far exceeds the organ donor pool. In our country, despite a large population the number of brain dead donors undergoing organ donation is very less (2% in our study).

AIMS

The present study was undertaken to address issues related to organ donation and share our experience for the same.

METHODS

A retrospective case record analysis of over 5 years from September 2007 to August 2012 was performed and the patients fulfilling brain death criterion as per Transplantation of Human Organs and Tissue (Amendment) Act were included. Patient demographics (age, sex), mode of injury, time from injury to the diagnosis of brain death, time from diagnosis of brain death to organ retrieval and complications were analysed.

STATISTICS ANALYSIS

Student's t test was used for parametric data and Chi square was used for categorical data.

RESULTS

Out of 205 patients who were identified as brain dead, only 10 patients became potential organ donors.

CONCLUSION

Aggressive donor management, increasing public awareness about the concept of organ donation, good communication between clinician and the family members and a well-trained team of transplant coordinators can help in improving the number of organ donations.

摘要

背景

由于器官接受者的等待名单远远超过器官捐赠者库,从脑死亡患者身上获取器官越来越受到关注。在我国,尽管人口众多,但进行器官捐赠的脑死亡捐赠者数量却非常少(在我们的研究中为2%)。

目的

开展本研究以解决与器官捐赠相关的问题并分享我们在此方面的经验。

方法

对2007年9月至2012年8月这5年多时间的病例记录进行回顾性分析,纳入符合《人体器官和组织移植(修订)法案》脑死亡标准的患者。分析患者的人口统计学特征(年龄、性别)、受伤方式、从受伤到脑死亡诊断的时间、从脑死亡诊断到器官获取的时间以及并发症情况。

统计学分析

参数数据采用学生t检验,分类数据采用卡方检验。

结果

在205名被确定为脑死亡的患者中,只有10名患者成为潜在的器官捐赠者。

结论

积极的捐赠者管理、提高公众对器官捐赠概念的认识、临床医生与家庭成员之间良好的沟通以及一支训练有素的移植协调员团队有助于增加器官捐赠的数量。

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Ethics and end-of-life care for adults in the intensive care unit.成人重症监护病房的伦理与临终关怀。
Lancet. 2010 Oct 16;376(9749):1347-53. doi: 10.1016/S0140-6736(10)60143-2. Epub 2010 Oct 11.
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Brain death and its implications for management of the potential organ donor.脑死亡及其对潜在器官捐献者管理的影响。
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Aggressive organ donor management significantly increases the number of organs available for transplantation.积极的器官捐献者管理显著增加了可用于移植的器官数量。
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What can be learned from brain-death models?从脑死亡模型中可以学到什么?
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Physiologic changes during brain stem death--lessons for management of the organ donor.脑干死亡期间的生理变化——器官捐献者管理的经验教训
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