Endo Yumi, Sugiura Hiroshi, Yamashita Hiroko, Takahashi Satoru, Yoshimoto Nobuyasu, Iwasa Mai, Asano Tomoko, Toyama Tatsuya
Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan.
Case Rep Oncol Med. 2013;2013:164761. doi: 10.1155/2013/164761. Epub 2013 Jul 30.
Myoepithelial carcinoma (malignant myoepithelioma) of the breast is a rare tumor, for which only a limited number of reports have been published. Most of the reports emphasized diagnosis and pathology but not biological behavior and treatment. We report a 61-year-old patient with breast myoepithelial carcinoma who developed locoregional and distant metastases and received many chemotherapy regimens. She presented with an elastic hard mass of the left breast. Breast conserving surgery was performed as part of both diagnosis and treatment. From the results of histological and immunohistochemical examinations, this case was considered to be a myoepithelial carcinoma. Fifteen months after the completion of adjuvant radiotherapy, distant metastasis of the left parasternal lymph node metastasis developed. She was treated by further excision and received a total of four regimens of chemotherapy including a combination of doxorubicin and cyclophosphamide. She received chemotherapy for 20 months after the diagnosis of metastasis.
乳腺肌上皮癌（恶性肌上皮瘤）是一种罕见肿瘤，关于它的报道仅有少数发表。大多数报道着重于诊断和病理学，而非生物学行为和治疗。我们报告一例61岁患乳腺肌上皮癌的患者，该患者出现了局部区域及远处转移，并接受了多种化疗方案。她表现为左乳有一个质地硬且有弹性的肿块。作为诊断和治疗的一部分，实施了保乳手术。根据组织学和免疫组化检查结果，此病例被诊断为肌上皮癌。辅助放疗结束15个月后，出现了左胸骨旁淋巴结远处转移。她接受了进一步切除治疗，并总共接受了四种化疗方案，包括多柔比星与环磷酰胺联合化疗。在诊断出转移后，她接受了20个月的化疗。
