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系统性红斑狼疮患者的听力损失

Hearing loss in patients with systemic lupus erythematosus.

作者信息

Abbasi Mahnaz, Yazdi Zohreh, Kazemifar Amir Mohammad, Bakhsh Zahra Zarin

机构信息

Qazvin University of Medical Sciences.

出版信息

Glob J Health Sci. 2013 Jun 15;5(5):102-6. doi: 10.5539/gjhs.v5n5p102.

Abstract

OBJECTIVES

Systemic lupus erythematosus has its unique complications which warrant careful examination and assessment during follow/up visits of patients. The present study was conducted to evaluate prevalence of hearing loss in patients with SLE.

MATERIALS & METHODS: At present a case- control study has been performed on 45 patients with SLE in a clinic of a teaching university hospital, Qazvin city, Iran. The patients were examined and evaluated for auditory and hearing problems as well as parameters related to their disease severity and progression. The control group was selected from the same clinic.

RESULTS

Five patients (11.1%) complained from hearing loss, 4 patients s (8.9%) complained from otorrhea, 3 patients (6.7%) had tinnitus in research group, moreover twelve patients (26.7%) in case group and 4 patients (8.9%) in control group had sensorineural hearing loss. The difference was found to be statistically significant. No statistical significant relationship was found between severity, age of onset, and duration of the disease, and the lab tests of the patients with hearing loss.

CONCLUSION

The present study implies that patients with systemic lupus erythematosus may develop sensorineural hearing loss during their course of the disease. It is recommended that audiology examination and/or audiometry become a part of routine follow/up studies of the patients.

摘要

目的

系统性红斑狼疮有其独特的并发症,在患者随访期间需要仔细检查和评估。本研究旨在评估系统性红斑狼疮患者听力损失的患病率。

材料与方法

目前在伊朗加兹温市一所教学大学医院的诊所对45例系统性红斑狼疮患者进行了病例对照研究。对患者进行了听觉和听力问题以及与其疾病严重程度和进展相关参数的检查和评估。对照组选自同一诊所。

结果

研究组中5例患者(11.1%)主诉听力损失,4例患者(8.9%)主诉耳漏,3例患者(6.7%)有耳鸣,此外病例组中有12例患者(26.7%)和对照组中有4例患者(8.9%)有感觉神经性听力损失。发现差异具有统计学意义。在听力损失患者的疾病严重程度、发病年龄、病程与实验室检查之间未发现统计学显著关系。

结论

本研究表明系统性红斑狼疮患者在疾病过程中可能发生感觉神经性听力损失。建议听力检查和/或听力测定成为患者常规随访研究的一部分。

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Auditory function in patients with systemic lupus erythematosus.系统性红斑狼疮患者的听觉功能
Auris Nasus Larynx. 2011 Feb;38(1):26-32. doi: 10.1016/j.anl.2010.04.008. Epub 2010 Jun 23.
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Chloroquine ototoxicity.氯喹耳毒性。
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