Guo Guang-hua
Department of Burns, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Zhonghua Shao Shang Za Zhi. 2013 Apr;29(2):134-8.
Although the study of inhalation injury is deepening gradually, its clinical treatment is still difficult, and its mortality rate remains high due to the complicated pathophysiologic characteristics. This article reviews the recent progress in research and treatment of inhalation injury, acute lung injury, and acute respiratory distress syndrome at home and abroad, focusing on the effect of mechanical ventilation models, including the non-invasive ventilation, lung protective ventilation, liquid ventilation, high frequency ventilation, on respiratory support in early stage of inhalation injury. The effects of medications for inhalation injury are summarized, and the prospect of stem cell therapy for inhalation injury is also discussed.
尽管对吸入性损伤的研究在逐渐深入,但其临床治疗仍然困难,由于其复杂的病理生理特征,死亡率仍然很高。本文综述了国内外在吸入性损伤、急性肺损伤和急性呼吸窘迫综合征的研究与治疗方面的最新进展,重点关注机械通气模式,包括无创通气、肺保护性通气、液体通气、高频通气,对吸入性损伤早期呼吸支持的作用。总结了治疗吸入性损伤的药物的作用,并讨论了干细胞治疗吸入性损伤的前景。