MMWR Morb Mortal Wkly Rep. 2013 Aug 30;62(34):694-6.
The Bacteroides fragilis group consists of species of obligate anaerobic bacteria that inhabit the human gut. They are among the leading pathogens isolated in the setting of intra-abdominal infections. B. fragilis strains, especially in the United States, are virtually always susceptible to metronidazole, carbapenems, and beta-lactam antibiotics. Although isolated cases of resistance to single agents have been reported, multidrug-resistant (MDR) B. fragilis strains are exceptionally rare. In May 2013, an MDR B. fragilis strain was isolated from the bloodstream and intra-abdominal abscesses of a patient who had recently received health care in India. This is only the second published case of MDR B. fragilis in the United States. This report summarizes the case and highlights the need for awareness of multidrug-resistant organisms (MDROs) in returning travelers who have received inpatient medical care outside the United States, both for timely implementation of proper infection control measures and to ensure administration of appropriate antimicrobials.
脆弱拟杆菌群由专性厌氧菌组成，栖息于人类肠道。它们是腹腔内感染中主要分离出的病原体之一。脆弱拟杆菌株，尤其是在美国，几乎对甲硝唑、碳青霉烯类和β-内酰胺类抗生素均敏感。虽然已报道有单一药物耐药的孤立病例，但多药耐药（MDR）脆弱拟杆菌株极为罕见。2013 年 5 月，从一位刚在印度接受过医疗保健的患者的血流和腹腔脓肿中分离出一株 MDR 脆弱拟杆菌。这是美国发表的第二例 MDR 脆弱拟杆菌感染。本报告总结了该病例，并强调了对从美国境外住院接受过医疗护理的归国旅行者中出现的多重耐药菌（MDRO）的认识，这对于及时实施适当的感染控制措施并确保使用适当的抗菌药物至关重要。
