使用突变组织培养细胞对环磷酸腺苷作用的研究。
Studies of cyclic AMP action using mutant tissue culture cells.
作者信息
Coffino P, Bourne H R, Insel P A, Melmon K L, Johnson G, Vigne J
出版信息
In Vitro. 1978 Jan;14(1):140-5. doi: 10.1007/BF02618180.
PMID:23989
Abstract
S49 mouse lymphoma cell mutants, each with a specific defect in its ability to generate or respond to cyclic AMP, have been isolated. Analysis of the properties of these cells has begun to provide information on complex and significant biologic problems related to the cyclic AMP system.
摘要
已分离出S49小鼠淋巴瘤细胞突变体，每个突变体在生成或响应环磷酸腺苷（cAMP）的能力上都有特定缺陷。对这些细胞特性的分析已开始提供与环磷酸腺苷系统相关的复杂且重要生物学问题的信息。
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