Kuo J F, Greengard P
Proc Natl Acad Sci U S A. 1969 Dec;64(4):1349-55. doi: 10.1073/pnas.64.4.1349.
Adenosine 3',5'-monophosphate-dependent protein kinase activity was found in about thirty sources including many mammalian tissues as well as species representative of eight different invertebrate phyla. The data support a unifying theory for the mechanism of action of adenosine 3',5'-monophosphate, namely that its many and diverse effects are mediated through activation of tissue-specific protein kinases.
在约三十种来源中发现了3',5'-环磷酸腺苷依赖性蛋白激酶活性,包括许多哺乳动物组织以及代表八个不同无脊椎动物门的物种。这些数据支持了关于3',5'-环磷酸腺苷作用机制的统一理论,即其众多不同的效应是通过激活组织特异性蛋白激酶介导的。