Storozhuk V M, Ivanova S F, Stezhka V V
Neirofiziologiia. 1990;22(3):337-47.
Responses of the sensorimotor cortex neurons to tactile and conditional sound stimuli have been investigated before and after serotonin and lysergoamide iontophoretic application. Three functional neuronal groups were distinguished according to their responses to unconditional and conditional stimuli. It was shown that serotonin application facilitated early and late impulse responses to tactile stimuli, facilitated and modulated impulse responses of many cortical neurons to conditional stimuli. Changes in responses to conditioning occurred during initial phase of the placing reaction and just after initiation of the conditional movement. Serotonin application promoted involving new neurons in response to sound. All these changes in the reactions developed with unsignificant background activity fluctuation. It is supposed that facilitation of neuronal responses caused by serotonin was linked with activation of excitatory receptors (S2). An increase of the background and evoked impulse activity following application of lysergoamide may depend on inhibitory serotonin receptors (S1B).
在血清素和麦角酰二乙胺离子电渗疗法应用前后，研究了感觉运动皮层神经元对触觉和条件性声音刺激的反应。根据对无条件和条件性刺激的反应，区分出三个功能性神经元组。结果表明，应用血清素促进了对触觉刺激的早期和晚期冲动反应，促进并调节了许多皮层神经元对条件性刺激的冲动反应。对条件作用的反应变化发生在放置反应的初始阶段以及条件性运动开始后不久。应用血清素促使新的神经元参与对声音的反应。所有这些反应变化都是在背景活动波动不显著的情况下发生的。据推测，血清素引起的神经元反应促进与兴奋性受体（S2）的激活有关。应用麦角酰二乙胺后背景和诱发冲动活动的增加可能取决于血清素抑制性受体（S1B）。
