Josten C, Glasmacher S, Franck A
Klinik und Poliklinik für Unfall-, Wiederherstellungs- und Plastische Chirurgie, Universität Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland.
Orthopade. 2013 Sep;42(9):755-64. doi: 10.1007/s00132-013-2070-8.
The number of patients with symptomatic metastases increases from year to year. Especially spinal metastases often lead to severe pain which often cannot be treated adequately by conservative treatment. Surgeons are confronted with the risk of instability, pathological fractures and neurological failure and the surgical treatment necessary in most cases is nowadays becoming an even greater challenge. The surgical procedure has changed considerably in recent years. The therapy is patient-individualized, the selection of implants and technology is adapted to the physical condition of the patient and the progression of the underlying disease. The main targets of the surgical treatment of spinal metastases have to be sufficient pain reduction with restoration of mobility as well as with the prevention of neurological deficits caused by progressive osteolysis. There are two minimally invasive stabilization procedures which can basically be applied. Under certain circumstances a single kyphoplasty/vertebroplasty procedure can be sufficient, in contrast to the possibility of short or long percutaneous posterior stabilization in combination with selective decompression of neural structures. These percutaneous surgical procedures currently have an important place in the surgical treatment of spinal metastases. The advantages are a less traumatic intervention for patients with advanced malignant diseases and poor general condition. Low intraoperative loss of blood means less intraoperative stress for the patient and minor surgical approaches lead to rapid mobilization and effective pain relief. As a result the hospital stay is shorter, adjuvant therapy can be started earlier and patients can be discharged sooner.
有症状转移的患者数量逐年增加。特别是脊柱转移瘤常常导致严重疼痛,而保守治疗往往无法充分缓解。外科医生面临着脊柱不稳定、病理性骨折和神经功能障碍的风险,如今在大多数情况下所需的手术治疗正成为一项更大的挑战。近年来手术方法有了很大改变。治疗是根据患者个体情况而定的,植入物和技术的选择要适应患者的身体状况和基础疾病的进展。脊柱转移瘤手术治疗的主要目标必须是充分减轻疼痛、恢复活动能力以及预防进行性骨质溶解导致的神经功能缺损。有两种基本可应用的微创稳定手术方法。在某些情况下,单次椎体后凸成形术/椎体成形术可能就足够了,与之相对的是短节段或长节段经皮后路稳定术结合神经结构选择性减压的可能性。这些经皮手术目前在脊柱转移瘤的手术治疗中占有重要地位。其优点是对于晚期恶性疾病且全身状况较差的患者,干预创伤较小。术中失血少意味着患者术中应激小,小的手术切口能使患者快速活动并有效缓解疼痛。因此住院时间缩短,辅助治疗可更早开始,患者能更快出院。