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[上颈椎(C0 - 2)的肿瘤与转移瘤。一项特殊挑战]

[Tumors and metastases of the upper cervical spine (C0-2). A special challenge].

作者信息

Jeszenszky D J, Haschtmann D, Pröbstl O, Kleinstück F S, Heyde C E, Fekete T F

机构信息

Wirbelsäulenchirurgie, Muskulo-Skelettal-Zentrum, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Schweiz.

出版信息

Orthopade. 2013 Sep;42(9):746-54. doi: 10.1007/s00132-013-2069-1.

DOI:10.1007/s00132-013-2069-1
PMID:23989592
Abstract

Tumors of the upper cervical spine are rare and represent less than 0.5 % of all spinal tumors. The types of tumor and the clinical presentation are as varied as the modalities used for treatment. The unique anatomy of the upper cervical spine with its high physical mobility means that biomechanical considerations and neighboring anatomical structures (e.g. vertebral artery, medulla oblongata, lower cranial nerves and pharynx) must be considered when creating a treatment plan. Finding a balance between complete tumor removal, the preservation and reestablishment of stability and function and the possible necessity for postoperative radiotherapy is of utmost importance and must be assessed on an individual basis. In this review paper some important points will be presented concerning the preparation of the patient, the planning of the operation and the surgical approach used in treating tumors of the craniocervical junction.

摘要

上颈椎肿瘤较为罕见,占所有脊柱肿瘤的比例不到0.5%。肿瘤类型和临床表现与治疗方式一样多种多样。上颈椎独特的解剖结构及其高活动度意味着,在制定治疗方案时必须考虑生物力学因素以及邻近的解剖结构(如椎动脉、延髓、低位颅神经和咽部)。在完全切除肿瘤、保留并重建稳定性和功能以及术后可能需要放疗之间找到平衡至关重要,且必须根据个体情况进行评估。在这篇综述文章中,将阐述一些关于患者准备、手术规划以及治疗颅颈交界区肿瘤所采用的手术入路的要点。

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本文引用的文献

1
[Radiological diagnostics of spinal tumors. Part 1: general tumor diagnostics and special diagnostics of extradural tumors].[脊柱肿瘤的放射诊断。第1部分:一般肿瘤诊断及硬膜外肿瘤的特殊诊断]
Orthopade. 2012 Aug;41(8):595-607. doi: 10.1007/s00132-012-1978-8.
2
[Vertebral stability in management of spinal metastases. Criteria and strategies for operative interventions].[脊柱转移瘤治疗中的椎体稳定性。手术干预的标准与策略]
Orthopade. 2012 Aug;41(8):623-31. doi: 10.1007/s00132-012-1908-9.
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[Management of spinal metastases, strategies and surgical indications].
Biomechanical evaluation of a novel integrated artificial axis: A finite element study.
一种新型一体化人工枢椎的生物力学评估:有限元研究
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[Surgical management of thoracolumbar spinal sarcoma].[胸腰椎脊柱肉瘤的外科治疗]
Orthopade. 2012 Aug;41(8):659-73. doi: 10.1007/s00132-012-1911-1.
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[Diagnostics and therapy of spinal metastases].[脊柱转移瘤的诊断与治疗]
Orthopade. 2011 Feb;40(2):185-93; quiz 194-5. doi: 10.1007/s00132-010-1738-6.
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Combined pre- and retrovascular extraoral approach for tumors at lateral mass of the atlas.经口前路及血管前置外联合入路切除寰椎侧块肿瘤。
Spine (Phila Pa 1976). 2011 Jan 15;36(2):129-36. doi: 10.1097/BRS.0b013e3181ce1ac8.
7
Intraarticular atlantooccipital fusion for the treatment of traumatic occipitocervical dislocation in a child: a new technique for selective stabilization with nine years follow-up.关节内寰枕融合术治疗儿童创伤性枕颈脱位:一种新的选择性稳定技术,随访 9 年。
Spine (Phila Pa 1976). 2010 May 1;35(10):E421-6. doi: 10.1097/BRS.0b013e3181c91fa1.
8
Metastases to the craniovertebral junction.颅颈交界区转移。
Neurosurgery. 2010 Mar;66(3 Suppl):113-8. doi: 10.1227/01.NEU.0000365829.97078.B2.
9
Craniovertebral junction lesions: our experience with the transoral surgical approach.颅颈交界区病变:我们经口手术入路的经验
Eur Spine J. 2009 Jun;18 Suppl 1(Suppl 1):13-9. doi: 10.1007/s00586-009-0988-7. Epub 2009 Apr 29.
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Primary malignant tumors of the spine.脊柱原发性恶性肿瘤。
Orthop Clin North Am. 2009 Jan;40(1):21-36, v. doi: 10.1016/j.ocl.2008.10.004.