Paiva Carlos Eduardo, Paiva Bianca Sakamoto Ribeiro, Yennurajalingam Sriram, Hui David
Department of Clinical Oncology, Barretos Cancer Hospital, Rua Antenor Duarte Villela, 1331, Barretos, CEP 14784-400, São Paulo, Brazil,
J Relig Health. 2014 Dec;53(6):1717-27. doi: 10.1007/s10943-013-9770-6.
Consecutive patients (n = 221) presenting for initial consultation at a palliative care outpatient clinic were prospectively interviewed and then followed until death. Individual prayer activity (IPA) and global religion scores were associated with quality of life, symptoms, inflammatory markers, and survival. Analyses were adjusted for whether patients were still receiving anti-neoplastic therapies (ANTs) or not. Higher religion scores were associated with lower levels of inflammation in advanced cancer patients still undergoing ANTs. Additionally, higher IPA was an independent good prognostic factor in patients on active ANTs. Further studies are necessary to confirm these findings and to investigate possible biological mechanisms involved.
对在姑息治疗门诊进行首次咨询的连续患者（n = 221）进行前瞻性访谈，然后随访直至死亡。个体祈祷活动（IPA）和整体宗教得分与生活质量、症状、炎症标志物及生存率相关。分析针对患者是否仍在接受抗肿瘤治疗（ANTs）进行了调整。较高的宗教得分与仍在接受ANTs的晚期癌症患者较低的炎症水平相关。此外，较高的IPA是正在接受积极ANTs治疗患者的独立良好预后因素。有必要进行进一步研究以证实这些发现并探究其中可能涉及的生物学机制。
