中国屠宰猪中一种新型的细小病毒1型（TTSuV1）亚基因型
A Novel Subgenotype of Torque teno Virus 1 (TTSuV1) in Slaughter Pigs in China.
作者信息
Huang Jinhai, Li Yi, Liu Mengmeng, Xia Yihe, Li Zhirong
机构信息
School of Chemical Engineering &Technology, Tianjin University, No. 92, Weijin Road, Nankai District, Tianjin, 300072, China,
出版信息
Food Environ Virol. 2013 Aug 30. doi: 10.1007/s12560-013-9126-0.
TTsuV1 can cause persistent infection and unidentified clinical signs in pigs. In this study, a survey of TTsuV1 prevalence was conducted in slaughter pigs from Henan, Liaoning, and Shandong provinces in China. A total of 180 swine lymphoid tissues were assayed by PCR with primers targeting the conserved 5'-untranslated region (5'-UTR). The results showed that a 17.8 % positive rate, and different genotypes were detected. TTSuV1 presented higher viral load and prevalence in inguinal lymph node than in submandibular lymph node samples. All TTsuV1 isolates have 84-100 % nucleotide sequence homology in the 5'-UTR region and can be grouped into three subgenotypes (TTsuV1, TTsuV1, and TTsuV1). Notably, the novel genetic subtype TTsuV1 was first reported in slaughter pigs.
猪圆环病毒1型（TTsuV1）可在猪群中引起持续性感染和不明临床症状。本研究对来自中国河南、辽宁和山东三省的屠宰猪进行了TTsuV1流行情况调查。采用针对保守5'-非翻译区（5'-UTR）的引物，通过聚合酶链反应（PCR）对180份猪淋巴组织进行检测。结果显示，阳性率为17.8%，且检测到不同基因型。与下颌下淋巴结样本相比，腹股沟淋巴结中TTsuV1的病毒载量和流行率更高。所有TTsuV1分离株在5'-UTR区域的核苷酸序列同源性为84%-100%，可分为三个亚基因型（TTsuV1、TTsuV1和TTsuV1）。值得注意的是，新型遗传亚型TTsuV1首次在屠宰猪中被报道。
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