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关于藤黄果 (-)-HCA 抗肥胖作用的最新研究进展。

Updates on Antiobesity Effect of Garcinia Origin (-)-HCA.

机构信息

School of Industrial Technology, University Science Malaysia, 11800 Penang, Malaysia.

出版信息

Evid Based Complement Alternat Med. 2013;2013:751658. doi: 10.1155/2013/751658. Epub 2013 Aug 6.

DOI:10.1155/2013/751658
PMID:23990846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3748738/
Abstract

Garcinia is a plant under the family of Clusiaceae that is commonly used as a flavouring agent. Various phytochemicals including flavonoids and organic acid have been identified in this plant. Among all types of organic acids, hydroxycitric acid or more specifically (-)-hydroxycitric acid has been identified as a potential supplement for weight management and as antiobesity agent. Various in vivo studies have contributed to the understanding of the anti-obesity effects of Garcinia/hydroxycitric acid via regulation of serotonin level and glucose uptake. Besides, it also helps to enhance fat oxidation while reducing de novo lipogenesis. However, results from clinical studies showed both negative and positive antiobesity effects of Garcinia/hydroxycitric acid. This review was prepared to summarise the update of chemical constituents, significance of in vivo/clinical anti-obesity effects, and the importance of the current market potential of Garcinia/hydroxycitric acid.

摘要

藤黄是藤黄科植物，通常用作调味剂。该植物中已鉴定出多种植物化学物质，包括类黄酮和有机酸。在所有类型的有机酸中，羟基柠檬酸或更具体地说（-）-羟基柠檬酸已被鉴定为一种用于体重管理和抗肥胖的潜在补充剂。各种体内研究有助于通过调节血清素水平和葡萄糖摄取来理解藤黄/羟基柠檬酸的抗肥胖作用。此外，它还有助于增强脂肪氧化，同时减少从头脂肪生成。然而，临床研究的结果显示藤黄/羟基柠檬酸具有正反两方面的抗肥胖作用。本综述旨在总结藤黄/羟基柠檬酸的化学成分更新、体内/临床抗肥胖作用的意义以及其当前市场潜力的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/3748738/fcd43ccde007/ECAM2013-751658.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/3748738/fcd43ccde007/ECAM2013-751658.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/3748738/fcd43ccde007/ECAM2013-751658.001.jpg

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