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游离腹壁下动脉穿支皮瓣(DIEP)乳房重建术中的失血量和输血率。引入新的预测因子。

Blood loss and transfusion rates in DIEP flap breast reconstruction. Introducing a new predictor.

机构信息

Burns and Plastic Surgery Unit, Whiston Hospital, Warrington Road, L35 5DR Liverpool, UK.

出版信息

J Plast Reconstr Aesthet Surg. 2013 Dec;66(12):1659-64. doi: 10.1016/j.bjps.2013.07.013. Epub 2013 Aug 29.

Abstract

BACKGROUND

The popularity of the DIEP flap has increased over the last decade. However, there is little information regarding the transfusion rates of this complex procedure. The current study reports the transfusion rates in patients who underwent DIEP flap reconstruction in our unit with an attempt to correlate significant blood loss with potential predictors such as the abdominal flap weight.

METHODS-MATERIAL: A retrospective review of 131 patients who underwent DIEP reconstruction was performed. Patients' characteristics, risk factors, incidence of blood transfusions, Hb drop and complications were reviewed. For statistical analysis the two-tailed Student t-test, chi-squared significance test and multiple regression model were used.

RESULTS

12 patients (9.1%) were transfused compared to 80.3% and 18.8% described in the literature. Definite association was found between the presence of a complication and transfusion. No correlation was found between age, obesity, chemotherapy and/or radiotherapy or tamoxifen treatment and blood loss. However, operation duration, complications and weight all found to have significant correlation. On average, every additional hour of surgery adds 0.25 g of Hb drop; the presence of a complication adds 0.45 g of Hb drop, and every extra gram of tissue removed from the abdomen adds an extra 0.001 g of Hb drop.

CONCLUSION

The different transfusion rates published reflect variations in surgical strategies, different operative technical details but mostly transfusion protocols applied in each unit. As a correlation with complications was found, it is quite important to identify predictors for significant blood loss to optimise the operation outcome which in our study are additional time of surgery, the presence of complication and increased flap weight.

摘要

背景

DIEP 皮瓣在过去十年中越来越受欢迎。然而,关于这种复杂手术的输血率的信息却很少。本研究报告了我们单位接受 DIEP 皮瓣重建的患者的输血率,并试图将大量失血与潜在的预测因素(如腹部皮瓣重量)相关联。

方法-材料:对 131 例接受 DIEP 重建的患者进行了回顾性研究。回顾了患者的特征、危险因素、输血发生率、Hb 下降和并发症。为了进行统计分析,使用了双尾学生 t 检验、卡方显著性检验和多元回归模型。

结果

12 例(9.1%)患者输血,而文献中描述的为 80.3%和 18.8%。存在并发症与输血之间存在明确的相关性。年龄、肥胖、化疗和/或放疗或他莫昔芬治疗与失血之间无相关性。然而,手术时间、并发症和体重均与失血有显著相关性。平均而言,手术每增加 1 小时,Hb 下降 0.25g;存在并发症时,Hb 下降 0.45g,腹部每多切除 1 克组织,Hb 下降 0.001g。

结论

不同的输血率反映了手术策略、不同的手术技术细节的变化,但主要是每个单位应用的输血方案。由于发现了与并发症的相关性,因此识别大量失血的预测因素以优化手术结果非常重要,在我们的研究中,这些预测因素是手术时间的延长、并发症的存在和皮瓣重量的增加。

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