Jaiswal Abhishek, Rashid Mahjabeen, Balek Mark, Park Chong
New York Hospital Queens, Weill Medical College of Cornell University, New York 11355, USA.
Indian Heart J. 2013 Jul-Aug;65(4):464-8. doi: 10.1016/j.ihj.2013.06.016. Epub 2013 Jul 12.
Acute myocardial infarction (AMI) in pregnancy is associated with high morbidity and mortality. Management of these patients can be challenging as little is known about the optimal management strategy. Medications routinely used may have harmful effects on the pregnancy outcome. In addition, AMI could occur in the absence of atherosclerotic disease. We describe optimal management strategy by eliciting the management of a 45-year-old female with ST segment elevation myocardial infarction. We recommend early use of coronary angiography to define the pathology in such cases. Radial artery assess should be preferred. Pregnant patients with AMI due to atherosclerotic disease should be given a 325 mg of aspirin and 600 mg of clopidogrel and either balloon angioplasty or bare metal stent should be used for revascularization. Percutaneous coronary intervention with heparin is preferred over bivalirudin and later should be reserved for patients with severe heparin allergy.
妊娠期急性心肌梗死(AMI)与高发病率和死亡率相关。这些患者的管理具有挑战性,因为对于最佳管理策略知之甚少。常规使用的药物可能对妊娠结局产生有害影响。此外,AMI可能在无动脉粥样硬化疾病的情况下发生。我们通过引出一名45岁女性ST段抬高型心肌梗死的管理来描述最佳管理策略。我们建议在此类病例中尽早使用冠状动脉造影来明确病理情况。应首选桡动脉评估。因动脉粥样硬化疾病导致AMI的孕妇应给予325毫克阿司匹林和600毫克氯吡格雷,并且应使用球囊血管成形术或裸金属支架进行血运重建。使用肝素进行经皮冠状动脉介入治疗优于比伐卢定,比伐卢定应留待对肝素严重过敏的患者使用。