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单切口经尿道中段吊带术:肥胖对结局的影响。

Single incision mid-urethral slings: impact of obesity on outcomes.

机构信息

Department of Obstetrics and Gynecology, Azienda Ospedaliera di Legnano, Ospedale "G. Fornaroli", Magenta, Italy.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2013 Oct;170(2):571-4. doi: 10.1016/j.ejogrb.2013.08.007. Epub 2013 Aug 11.

DOI:10.1016/j.ejogrb.2013.08.007
PMID:23993134
Abstract

OBJECTIVES

To assess the potential impact of obesity on the success rate of single incision slings (SIS).

STUDY DESIGN

This was a retrospective cohort study of women who underwent the SIS procedure for primary stress urinary incontinence. Women were divided into three different groups by body mass index (BMI) according to the WHO classification. The International Consultation on Incontinence-short form (ICIQ-SF), Women Irritative Prostate Symptoms Score (W-IPSS), Patient Global Impression of Severity (PGI-S) and Patient Global Impression of Improvement (PGI-I) questionnaires were used. Objective and subjective outcomes were the primary outcome measures of the study. SPSS software was used for data analysis.

RESULTS

206 patients who underwent the SIS procedure were reviewed. At 1 year follow-up there were 196 women available for the analysis: 69 were normal weight subjects, 91 overweight and 36 obese. Patients in all BMI groups reported a significant improvement in their condition. Nevertheless there was a trend towards lesser objective efficacy of SIS with increasing body weight, with a significant difference between obese women and normal subjects: 75% vs 91.3%, p=0.049; OR 3.74 (95% CI 1.19-11.76). Analysis of the ICIQ-SF and PGI-I showed significant lower mean ± SD improvement in obese women when compared with their normal or overweight counterparts, together with a significantly lower number of obese patients reporting themselves as very much improved or much improved.

CONCLUSIONS

Single incision slings seem to be an effective treatment regardless of BMI, but obese women had nearly 4 times the odds of objective failure as compared to normal weight women.

摘要

目的

评估肥胖对单切口吊带(SIS)成功率的潜在影响。

研究设计

这是一项针对因原发性压力性尿失禁而接受 SIS 手术的女性的回顾性队列研究。根据世界卫生组织(WHO)分类,女性按体重指数(BMI)分为三组。使用国际尿失禁咨询问卷-短表(ICIQ-SF)、女性刺激性前列腺症状评分(W-IPSS)、患者总体严重程度评分(PGI-S)和患者总体改善评分(PGI-I)问卷。客观和主观结果是本研究的主要结局指标。使用 SPSS 软件进行数据分析。

结果

共回顾了 206 例接受 SIS 手术的患者。在 1 年随访时,有 196 名女性可进行分析:69 名是正常体重患者,91 名超重,36 名肥胖。所有 BMI 组的患者均报告病情显著改善。然而,随着体重的增加,SIS 的客观疗效呈下降趋势,肥胖女性与正常体重女性之间存在显著差异:75%对 91.3%,p=0.049;OR 3.74(95%CI 1.19-11.76)。ICIQ-SF 和 PGI-I 分析显示,与正常体重或超重女性相比,肥胖女性的平均改善程度明显较低,且报告自己非常改善或明显改善的肥胖女性人数明显较少。

结论

单切口吊带似乎是一种有效的治疗方法,与 BMI 无关,但肥胖女性的客观失败几率是正常体重女性的近 4 倍。

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