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超重对压力性尿失禁患者中段尿道吊带术疗效及并发症的影响:一项系统评价和荟萃分析

The impact of overweight in the efficiency and complications of midurethral sling in patients with stress urinary incontinence: a systematic review and meta-analysis.

作者信息

Sun Yi, Lei Guo-Lin, Tang Cai, Yang Lu, Shen Hong, Wei Qiang

机构信息

Department of Urology, West China Hospital of Sichuan University, No.37 Guoxue Xiang, Chengdu, 610041, Sichuan, China.

Department of Urology, People's Hospital of Jianyang City, Yiyuan Road, Jianyang, Sichuan, China.

出版信息

Int Urol Nephrol. 2018 Sep;50(9):1597-1606. doi: 10.1007/s11255-018-1928-4. Epub 2018 Jul 14.

DOI:10.1007/s11255-018-1928-4
PMID:30008144
Abstract

AIMS

To compare the efficiency and complications of normal weight and overweight women with stress urinary incontinence (SUI) after surgery.

METHODS

We searched the PubMed, Embase, and Cochrane Library Databases to identify all compared results, including those involving the terms normal weight, overweight, body mass index (BMI), and SUI. After treatment with surgery, the efficiency (subjective cure rate, objective cure rate, UDI-6, and IIQ-7) and complications were compared between the normal weight and overweight groups.

RESULTS

The study inclusion criteria were met by 20 studies involving 3829 patients. The data synthesized from these studies indicated that the subjective and objective cure rates in the normal weight group were significantly more effective than those in the overweight group (RR 1.07; 95% CI 1.04-1.10; P < 0.00001; RR 1.24; 95% CI 1.18-1.30; P < 0.00001), while the IIQ-7 and UDI-6 were no different between the two groups (MD 0.07; 95% CI - 1.44 to 1.58; P = 0.93; MD 0.18; 95% CI - 1.24 to 1.60; P = 0.81). For the data of complications, only the urgency was more in the overweight group (RR 0.68, 95% CI 0.55-0.84, P = 0.0003).

CONCLUSIONS

The objective success rate and subjective success rate of the surgery were higher in normal weight patients than those in overweight patients. Also, the side effects between the two groups were not significantly different.

摘要

目的

比较体重正常和超重的压力性尿失禁(SUI)女性术后的疗效及并发症。

方法

检索PubMed、Embase和Cochrane图书馆数据库,以确定所有比较结果,包括涉及体重正常、超重、体重指数(BMI)和SUI等术语的结果。手术治疗后,比较体重正常组和超重组的疗效(主观治愈率、客观治愈率、UDI - 6和IIQ - 7)及并发症。

结果

20项研究纳入3829例患者,符合研究纳入标准。这些研究综合的数据表明,体重正常组的主观和客观治愈率显著高于超重组(RR 1.07;95% CI 1.04 - 1.10;P < 0.00001;RR 1.24;95% CI 1.18 - 1.30;P < 0.00001),而两组间IIQ - 7和UDI - 6无差异(MD 0.07;95% CI - 1.44至1.58;P = 0.93;MD 0.18;95% CI - 1.24至1.60;P = 0.81)。关于并发症数据,仅超重组尿急情况更多(RR 0.68,95% CI 0.55 - 0.84,P = 0.0003)。

结论

体重正常患者手术的客观成功率和主观成功率高于超重患者。此外,两组间副作用无显著差异。

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本文引用的文献

1
A comperative study for short-term surgical outcomes of midurethral sling procedures in obese and non-obese women with stress urinary incontinence.肥胖与非肥胖压力性尿失禁女性患者中尿道吊带手术短期手术效果的比较研究
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Five years after midurethral sling surgery for stress incontinence: obesity continues to have an impact on outcomes.治疗压力性尿失禁的中段尿道吊带手术后五年:肥胖持续影响治疗效果。
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Objective efficacy of the tension-free vaginal tape in obese/morbidly obese women versus non-obese women, at median five year follow up.
无张力阴道吊带术在肥胖/病态肥胖女性与非肥胖女性中的客观疗效,中位随访期为五年。
Aust N Z J Obstet Gynaecol. 2016 Dec;56(6):628-632. doi: 10.1111/ajo.12516. Epub 2016 Aug 17.
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The impact of obesity on outcomes and complications after top-down retropubic midurethral sling.
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Effectiveness of Transobturator Tape Procedure in Obese and Severely Obese Women: 3-Year Follow-up.经闭孔尿道中段吊带术在肥胖及重度肥胖女性中的疗效:3年随访
Urology. 2015 Aug;86(2):244-8. doi: 10.1016/j.urology.2015.03.048. Epub 2015 Jul 18.
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The long-term influence of body mass index on the success rate of mid-urethral sling surgery among women with stress urinary incontinence or stress-predominant mixed incontinence: comparisons between retropubic and transobturator approaches.体重指数对压力性尿失禁或以压力性为主的混合性尿失禁女性中尿道吊带手术成功率的长期影响:耻骨后途径与经闭孔途径的比较
PLoS One. 2014 Nov 21;9(11):e113517. doi: 10.1371/journal.pone.0113517. eCollection 2014.
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Twelve-month outcomes following midurethral sling procedures for stress incontinence: impact of obesity.中尿道吊带术治疗压力性尿失禁 12 个月的结果:肥胖的影响。
BJOG. 2015 Nov;122(12):1705-12. doi: 10.1111/1471-0528.13132. Epub 2014 Oct 15.
8
Urinary incontinence in women: a comprehensive review of the pathophysiology, diagnosis and treatment.女性尿失禁:病理生理学、诊断与治疗的综合综述
Minerva Ginecol. 2014 Oct;66(5):469-78. Epub 2014 Jul 31.
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The direct and indirect costs of both overweight and obesity: a systematic review.超重和肥胖的直接及间接成本:一项系统综述
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BMC Urol. 2014 Feb 20;14:20. doi: 10.1186/1471-2490-14-20.