Spritzer C E, Sostman H D, Wilkes D C, Coleman R E
Department of Radiology, Duke University Medical Center, Durham, NC 27710.
Radiology. 1990 Oct;177(1):235-41. doi: 10.1148/radiology.177.1.2399324.
The medical records of 66 patients who underwent evaluation for possible deep venous thrombosis (DVT) by means of gradient-echo (GRE) magnetic resonance (MR) imaging were reviewed. Confirmatory venograms were obtained in 26 patients; in the other 40, the accuracy of GRE MR imaging was assessed by means of clinical follow-up, which ranged from 1 to 23 months (mean, 7.7 months). Findings in GRE MR images were negative in 42 patients (64%) and positive in 24 patients (36%). In patients who underwent confirmatory venography, the sensitivity of GRE MR imaging was 100% and the specificity was 92.9%. No patient with a negative GRE MR study developed DVT or pulmonary emboli during the follow-up period. Although seven patients in this group died, the single autopsy showed no evidence of pulmonary embolism, and no clinical evidence existed to suggest that pulmonary embolism was the cause of death in any of the other six patients. It is concluded that GRE MR imaging is an accurate, noninvasive means of detecting DVT.
回顾了66例接受梯度回波（GRE）磁共振（MR）成像评估可能存在深静脉血栓形成（DVT）患者的病历。26例患者进行了确定性静脉造影；另外40例患者通过临床随访评估GRE MR成像的准确性，随访时间为1至23个月（平均7.7个月）。GRE MR图像结果在42例患者（64%）中为阴性，在24例患者（36%）中为阳性。在接受确定性静脉造影的患者中，GRE MR成像的敏感性为100%，特异性为92.9%。GRE MR检查结果为阴性的患者在随访期间均未发生DVT或肺栓塞。尽管该组中有7例患者死亡，但单次尸检未显示肺栓塞证据，且无临床证据表明其他6例患者中有任何一例的死亡原因是肺栓塞。结论是GRE MR成像是检测DVT的一种准确、无创的方法。
