Edelman R R, Mattle H P, Wallner B, Bajakian R, Kleefield J, Kent C, Skillman J J, Mendel J B, Atkinson D J
Department of Radiology, Beth Israel Hospital, Boston, MA.
Radiology. 1990 Oct;177(1):45-50. doi: 10.1148/radiology.177.1.2399337.
The authors evaluated the accuracy of "black blood" magnetic resonance (MR) angiography for depicting disease involving the extracranial carotid arteries. Two- and three-dimensional flow-compensated gradient-echo sequences were employed to create "bright blood" images. A thin-section spin-echo sequence with flow presaturation allowed the creation of black blood images. Projection angiograms were made from bright and black blood images with application of a maximum- or minimum-intensity projection algorithm, respectively. These methods were used in 13 healthy volunteers and 17 patients, and a prospective blinded comparison of MR angiography and conventional angiography was performed. Normal carotid arteries were well shown with both bright and black blood methods; in patients, both methods were sensitive for detecting carotid disease. However, bright blood angiography exaggerated the severity of carotid lesions in 13 of 33 arteries, mostly in severe disease; this problem was not encountered with black blood angiography. The authors conclude that bright blood angiography is a sensitive method for screening carotid disease; when a significant abnormality is found, black blood angiography should be performed for more precise delineation of the lesion.
作者评估了“黑血”磁共振（MR）血管造影术描绘颅外颈动脉疾病的准确性。采用二维和三维血流补偿梯度回波序列来生成“亮血”图像。带有血流预饱和的薄层自旋回波序列可生成黑血图像。分别应用最大强度投影算法或最小强度投影算法，从亮血和黑血图像制作投影血管造影。这些方法应用于13名健康志愿者和17名患者，并对MR血管造影和传统血管造影进行了前瞻性双盲比较。正常颈动脉在亮血和黑血方法中均显示良好；在患者中，两种方法对检测颈动脉疾病均敏感。然而，亮血血管造影在33条动脉中的13条夸大了颈动脉病变的严重程度，主要是在严重疾病中；黑血血管造影未出现此问题。作者得出结论，亮血血管造影是筛查颈动脉疾病的一种敏感方法；当发现明显异常时，应进行黑血血管造影以更精确地描绘病变。
