Dirix Piet, Joniau Steven, Van den Bergh Laura, Isebaert Sofie, Oyen Raymond, Deroose Christophe M, Lerut Evelyne, Haustermans Karin
Department of Radiation Oncology, University Hospitals Leuven, Belgium; Department of Oncology, KU Leuven, Belgium.
Department of Urology, University Hospitals Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Belgium.
Radiother Oncol. 2014 Jan;110(1):45-54. doi: 10.1016/j.radonc.2013.06.046. Epub 2013 Aug 27.
The role of elective radiotherapy of the pelvic nodal regions in clinically node-negative prostate cancer patients remains highly controversial. This review will address the difficulty of non-invasive nodal staging, even with more advanced imaging techniques, and will show that surgical staging still finds a relatively high percentage of patients with intermediate- or high-risk prostate cancer that have microscopic tumor invasion in the pelvic nodes. Finally, an overview of the current literature on elective pelvic irradiation will be provided.
盆腔淋巴结区域选择性放疗在临床淋巴结阴性前列腺癌患者中的作用仍极具争议。本综述将探讨即使采用更先进的成像技术进行非侵入性淋巴结分期的困难，并将表明手术分期仍能发现相当比例的中高危前列腺癌患者盆腔淋巴结存在微小肿瘤浸润。最后，将提供关于选择性盆腔照射的当前文献综述。
