Sow O, Diallo M P, Camara B, Diallo M B, Diallo A, Boissinot E, Lemarié E
Service de Pneumologie, CHU Ignace Deen, Conakry, République de Guinée.
Rev Mal Respir. 1990;7(4):355-60.
A study of tuberculous disease was carried out in children aged 5 to 13 years old who were first year pupils in primary schools in the town of Conakry (Republic of Guinae) with a view to determining the annual risk of tuberculous infection. In total 4,198 children distributed throughout 15 schools were tested after first looking for BCG vaccination scars. In the sample tested 1,444 children (34.4%) had vaccination scars and 2,754 (65.6%) did not. Amongst the 1,444 children with BCG scars, 1,367 (94.7%) were reviewed 72 hours after one unit of tuberculin RT 23 to have the skin reaction RDI read. Amongst these 210 (15.4%) had an area of induration greater than 6 m.m. diameter. Amongst 2,754 children who did not have BCG scars 2,655 (96.4%) were reviewed for the reading of the IDR: 330 children (12.8%) had an area of induration greater than 6 m.m. diameter. The percentage of children with an IDR greater than 6 m.m. as well as the mean diameter of induration was significantly greater in the group with a vaccination scar. The age of the children influenced the size of the induration. A factorial analysis revealed at the same time an age factor and a significant scar factor. Calculations from the prevalence of areas of induration with diameter greater than 6 m.m. in non-vaccinated children revealed an annual risk of infection of 1.52. A number of cases of pulmonary tuberculosis with positive microscopy in Conakry town is estimated at 90 per 100,000 inhabitants.
在几内亚共和国科纳克里镇对5至13岁的小学一年级学生进行了一项结核病研究，目的是确定结核感染的年度风险。在寻找卡介苗接种疤痕后，对分布在15所学校的4198名儿童进行了检测。在检测的样本中，1444名儿童（34.4%）有接种疤痕，2754名（65.6%）没有。在1444名有卡介苗疤痕的儿童中，1367名（94.7%）在注射一单位结核菌素RT 23后72小时接受复查，以读取皮肤反应RDI。其中210名（15.4%）硬结面积大于6毫米直径。在2754名没有卡介苗疤痕的儿童中，2655名（96.4%）接受了IDR读数复查：330名儿童（12.8%）硬结面积大于6毫米直径。有接种疤痕的儿童组中，IDR大于6毫米的儿童百分比以及硬结平均直径明显更高。儿童的年龄影响硬结大小。因子分析同时揭示了年龄因素和显著的疤痕因素。根据未接种疫苗儿童中直径大于6毫米的硬结面积患病率计算得出，年度感染风险为1.52。科纳克里镇显微镜检查呈阳性的肺结核病例估计为每10万居民90例。
