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一种用于检测急性脱水的综合尿液分析工具。

An aggregate urine analysis tool to detect acute dehydration.

机构信息

Dept. of Anesthesiology, Linköping University, Linköping, Sweden.

出版信息

Int J Sport Nutr Exerc Metab. 2013 Aug;23(4):303-11.

Abstract

PURPOSE

Urine sampling has previously been evaluated for detecting dehydration in young male athletes. The present study investigated whether urine analysis can serve as a measure of dehydration in men and women of a wide age span.

METHODS

Urine sampling and body weight measurement were undertaken before and after recreational physical exercise (median time: 90 min) in 57 volunteers age 17-69 years (mean age: 42). Urine analysis included urine color, osmolality, specific gravity, and creatinine.

RESULTS

The volunteers' body weight decreased 1.1% (mean) while they exercised. There were strong correlations between all 4 urinary markers of dehydration (r = .73-.84, p < .001). Researchers constructed a composite dehydration index graded from 1 to 6 based on these markers. This index changed from 2.70 before exercising to 3.55 after exercising, which corresponded to dehydration of 1.0% as given by a preliminary reference curve based on seven previous studies in athletes. Men were slightly dehydrated at baseline (mean: 1.9%) compared with women (mean: 0.7%; p < .001), though age had no influence on the results. A final reference curve that considered both the present results and the 7 previous studies was constructed in which exercise-induced weight loss (x) was predicted by the exponential equation x = 0.20 dehydration index1.86.

CONCLUSION

Urine sampling can be used to estimate weight loss due to dehydration in adults up to age 70. A robust dehydration index based on four indicators reduces the influence of confounders.

摘要

目的

尿液采样此前已被评估用于检测年轻男性运动员的脱水情况。本研究旨在调查尿液分析是否可作为衡量年龄跨度较大的男性和女性脱水的一种手段。

方法

57 名志愿者(年龄 17-69 岁,平均年龄 42 岁)在进行休闲体育锻炼前后进行了尿液采样和体重测量(中位数时间:90 分钟)。尿液分析包括尿液颜色、渗透压、比重和肌酐。

结果

志愿者在锻炼过程中体重平均下降 1.1%。所有 4 种尿液脱水标志物之间均存在强相关性(r =.73-.84,p <.001)。研究人员根据这些标志物构建了一个从 1 到 6 级的综合脱水指数。该指数从锻炼前的 2.70 变为锻炼后的 3.55,这与基于 7 项先前运动员研究的初步参考曲线所示的 1.0%的脱水程度相对应。与女性(平均 0.7%;p <.001)相比,男性在基线时略有脱水(平均:1.9%),但年龄对结果没有影响。考虑到本研究结果和之前的 7 项研究,构建了最终的参考曲线,其中运动引起的体重减轻(x)可以通过指数方程 x = 0.20 脱水指数 1.86 来预测。

结论

尿液采样可用于估计 70 岁以下成年人因脱水导致的体重减轻。基于 4 个指标的可靠脱水指数可减少混杂因素的影响。

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