层层组装多层多糖包覆的磁性纳米粒子用于糖肽的选择性富集。
Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides.
机构信息
Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Shanghai 200237, China.
出版信息
Chem Commun (Camb). 2013 Oct 18;49(81):9284-6. doi: 10.1039/c3cc45008b.
PMID:23995097
Abstract
Magnetic nanoparticles (MNPs) coated with multilayer polysaccharide shells have been fabricated using a layer-by-layer approach via the alternate deposition of hyaluronan (HA) and chitosan (CS) onto the surface, and the hydrophilic materials were utilized for effective and selective enrichment of glycopeptides in biological samples.
摘要
采用层层自组装法在磁性纳米粒子（MNPs）表面包覆多层多糖壳，通过交替沉积透明质酸（HA）和壳聚糖（CS），利用亲水性材料有效且选择性地从生物样品中富集糖肽。
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