Eijzenga Willem, Hahn Daniela E E, Aaronson Neil K, Kluijt Irma, Bleiker Eveline M A
Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066, CX, Amsterdam, The Netherlands.
J Genet Couns. 2014 Apr;23(2):133-46. doi: 10.1007/s10897-013-9649-4. Epub 2013 Aug 31.
Approximately 25% of individuals undergoing genetic counseling for cancer experiences clinically relevant levels of distress, anxiety and/or depression. However, these general psychological outcomes that are used in many studies do not provide detailed information on the specific psychosocial problems experienced by counselees. The aim of this review was to investigate the specific psychosocial issues encountered by individuals undergoing genetic counseling for cancer, and to identify overarching themes across these issues. A literature search was performed, using four electronic databases (PubMed, PsychInfo, CINAHL and Embase). Papers published between January 2000 and January 2013 were selected using combinations, and related indexing terms of the keywords: 'genetic counseling', 'psychology' and 'cancer'. In total, 25 articles met our inclusion criteria. We identified the specific issues addressed by these papers, and used meta-ethnography to identify the following six overarching themes: coping with cancer risk, practical issues, family issues, children-related issues, living with cancer, and emotions. A large overlap in the specific issues and themes was found between these studies, suggesting that research on specific psychosocial problems within genetic counseling has reached a point of saturation. As a next step, efforts should be made to detect and monitor these problems of counselees at an early stage within the genetic counseling process.
在接受癌症遗传咨询的个体中，约25%经历了具有临床意义的痛苦、焦虑和/或抑郁水平。然而，许多研究中使用的这些一般心理结果并未提供有关咨询对象所经历的具体心理社会问题的详细信息。本综述的目的是调查接受癌症遗传咨询的个体所遇到的具体心理社会问题，并确定这些问题的总体主题。使用四个电子数据库（PubMed、PsychInfo、CINAHL和Embase）进行了文献检索。通过组合使用关键词“遗传咨询”、“心理学”和“癌症”以及相关索引词，筛选出2000年1月至2013年1月发表的论文。共有25篇文章符合我们的纳入标准。我们确定了这些论文所涉及的具体问题，并使用元民族志确定了以下六个总体主题：应对癌症风险、实际问题、家庭问题、儿童相关问题、与癌症共存以及情绪。这些研究在具体问题和主题上存在很大重叠，这表明遗传咨询中关于具体心理社会问题的研究已达到饱和点。下一步，应努力在遗传咨询过程的早期阶段检测和监测咨询对象的这些问题。
